Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation - Zhang, Daoxiang; Wang, Yongbin; Shi, Zhimin; Liu, Jingyi; Sun, Pan; Hou, Xiaodan; Zhang, Jian; Zhao, Shimin; Zhou, Binhua P.; Mi, Jun (Cell reports (Cambridge), 2015)
Keywords: Animals; Cells, Cultured; Colonic Neoplasms - metabolism; Colonic Neoplasms - pathology; Down-Regulation - drug effects; Electron Transport Complex I - metabolism; Fibroblasts - cytology; Fibroblasts - drug effects; Fibroblasts - metabolism; Glucose - metabolism; Glycolysis - drug effects; Humans; Hypoxia-Inducible Factor 1, alpha Subunit - metabolism; Isocitrate Dehydrogenase - antagonists & inhibitors; Isocitrate Dehydrogenase - genetics; Isocitrate Dehydrogenase - metabolism; Ketoglutaric Acids - metabolism; Metabolic Engineering; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs - metabolism; Oxidative Phosphorylation; Phosphorylation; Platelet-Derived Growth Factor - pharmacology; Prolyl Hydroxylases - metabolism; RNA, Small Interfering - metabolism; Transforming Growth Factor beta1 - pharmacology; Up-Regulation - drug effects