Multi-scale and multi-parametric radiomics of gadoxetate disodium–enhanced MRI predicts microvascular invasion and outcome in patients with solitary hepatocellular carcinoma ≤ 5 cm

• Published in: European radiology Vol. 31; no. 7; pp. 4824 - 4838
• Main Authors: Chong, Huan-Huan, Yang, Li, Sheng, Ruo-Fan, Yu, Yang-Li, Wu, Di-Jia, Rao, Sheng-Xiang, Yang, Chun, Zeng, Meng-Su
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.07.2021; Springer Nature B.V
• Subjects: Alanine; Alanine transaminase; Alkaline phosphatase; Bilirubin; Biomarkers; Blood vessels; Diagnostic Radiology; Feature extraction; Hepatobiliary-Pancreas; Hepatocellular carcinoma; Imaging; Internal Medicine; Interventional Radiology; Invasiveness; Liver cancer; Magnetic resonance imaging; Medicine; Medicine & Public Health; Microvasculature; Multivariate analysis; Neuroradiology; Nomograms; Prediction models; Radiology; Radiomics; Regression analysis; Risk analysis; Risk factors; Tissue analysis; Ultrasound; α-Fetoprotein; Magnetic resonance imaging; Hepatocellular carcinoma; Neoplasm recurrence

Objectives To develop radiomics-based nomograms for preoperative microvascular invasion (MVI) and recurrence-free survival (RFS) prediction in patients with solitary hepatocellular carcinoma (HCC) ≤ 5 cm. Methods Between March 2012 and September 2019, 356 patients with pathologically confirmed solit...