Erythrocyte Indices and Hemoglobin Analysis for α-Thalassemia Screening in an Area with High Carrying Rate

• Published in: Indian journal of hematology & blood transfusion Vol. 38; no. 2; pp. 352 - 358
• Main Authors: Zheng, Lin, Huang, Hailong, Wu, Xiaoqing, Shen, Qingmei, Chen, Meihuan, Wang, Meiying, Su, Linjuan, Xu, Liangpu
• Format: Journal Article
• Language: English
• Published: New Delhi Springer India 01.04.2022; Springer Nature B.V
• Subjects: Blood diseases; Blood Transfusion Medicine; Diagnostic tests; Erythrocytes; Hematology; Hemoglobin; Human Genetics; Medical screening; Medicine; Medicine & Public Health; Oncology; Original; Original Article; α-thalassemia; Hemoglobin A; Mean corpuscular volume; Mean corpuscular hemoglobin; Hemoglobin A2

Carriers of α-thalassemia exhibit hypochromic microcytosis with mean corpuscular volume (MCV) < 80 fL, mean corpuscular hemoglobin (MCH) < 27 pg, and reduced hemoglobin A 2 (HbA 2 ). We studied the distribution and diagnostic efficiencies of these indicators and their combinations in patients...