Neuroanatomical correlates of apathy and disinhibition in behavioural variant frontotemporal dementia
Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioral (on Frontal Systems Behav...
Saved in:
| Published in | Brain imaging and behavior Vol. 14; no. 5; pp. 2004 - 2011 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer US
01.10.2020
Springer Nature B.V |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1931-7557 1931-7565 1931-7565 |
| DOI | 10.1007/s11682-019-00150-3 |
Cover
| Abstract | Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioral (on Frontal Systems Behavior (FrSBe) Scale), cortical volume (on voxel-based morphometry (VBM)) and tract based spatial fractional anisotropy ((FA) on magnetic resonance imaging (MRI), allowing examination of the neural correlates of apathy and disinhibition. The patients with bvFTD had predominant grey matter loss and corresponding white matter fractional anisotropy reduction in the frontal and temporal lobe compared to the controls. Grey matter loss in frontal, temporal and limbic structures correlated with apathy and degeneration in temporal limbic brain areas correlated with disinhibition. FA changes in inferior fronto-occipital fasciculus and forceps minor correlated with apathy and fibre integrity changes in the superior longitudinal fasciculus correlated with disinhibition. The current study suggests that apathy and disinhibition arises due to changes in the frontal, temporal and limbic brain areas in bvFTD. |
|---|---|
| AbstractList | Neuroanatomical correlates of apathy and disinhibition, behavioural abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remains unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioural (on Frontal Systems Behaviour (FrSBe) Scale), cortical volume (on voxel-based morphometry (VBM)) and tract based spatial fractional anisotropy ((FA) on magnetic resonance imaging (MRI), allowing examination of the neural correlates of apathy and disinhibition. The patients with bvFTD had predominant grey matter loss and corresponding white matter fractional anisotropy reductions in the frontal and temporal lobe compared to the controls. Grey matter loss in frontal, temporal and limbic structures correlated with apathy and degeneration in temporal limbic brain areas correlated with disinhibition. FA changes in inferior fronto-occipital fasciculus and forceps minor correlated with apathy and fibre integrity changes in the superior longitudinal fasciculus correlated with disinhibition. The current study suggests that apathy and disinhibition arises due to changes in the frontal, temporal and limbic brain cortices in bvFTD. Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioral (on Frontal Systems Behavior (FrSBe) Scale), cortical volume (on voxel-based morphometry (VBM)) and tract based spatial fractional anisotropy ((FA) on magnetic resonance imaging (MRI), allowing examination of the neural correlates of apathy and disinhibition. The patients with bvFTD had predominant grey matter loss and corresponding white matter fractional anisotropy reduction in the frontal and temporal lobe compared to the controls. Grey matter loss in frontal, temporal and limbic structures correlated with apathy and degeneration in temporal limbic brain areas correlated with disinhibition. FA changes in inferior fronto-occipital fasciculus and forceps minor correlated with apathy and fibre integrity changes in the superior longitudinal fasciculus correlated with disinhibition. The current study suggests that apathy and disinhibition arises due to changes in the frontal, temporal and limbic brain areas in bvFTD.Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioral (on Frontal Systems Behavior (FrSBe) Scale), cortical volume (on voxel-based morphometry (VBM)) and tract based spatial fractional anisotropy ((FA) on magnetic resonance imaging (MRI), allowing examination of the neural correlates of apathy and disinhibition. The patients with bvFTD had predominant grey matter loss and corresponding white matter fractional anisotropy reduction in the frontal and temporal lobe compared to the controls. Grey matter loss in frontal, temporal and limbic structures correlated with apathy and degeneration in temporal limbic brain areas correlated with disinhibition. FA changes in inferior fronto-occipital fasciculus and forceps minor correlated with apathy and fibre integrity changes in the superior longitudinal fasciculus correlated with disinhibition. The current study suggests that apathy and disinhibition arises due to changes in the frontal, temporal and limbic brain areas in bvFTD. Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioral (on Frontal Systems Behavior (FrSBe) Scale), cortical volume (on voxel-based morphometry (VBM)) and tract based spatial fractional anisotropy ((FA) on magnetic resonance imaging (MRI), allowing examination of the neural correlates of apathy and disinhibition. The patients with bvFTD had predominant grey matter loss and corresponding white matter fractional anisotropy reduction in the frontal and temporal lobe compared to the controls. Grey matter loss in frontal, temporal and limbic structures correlated with apathy and degeneration in temporal limbic brain areas correlated with disinhibition. FA changes in inferior fronto-occipital fasciculus and forceps minor correlated with apathy and fibre integrity changes in the superior longitudinal fasciculus correlated with disinhibition. The current study suggests that apathy and disinhibition arises due to changes in the frontal, temporal and limbic brain areas in bvFTD. Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this study 45 participants (25 bvFTD patients and 20 controls) provided data on clinical, neuropsychological, behavioral (on Frontal Systems Behavior (FrSBe) Scale), cortical volume (on voxel-based morphometry (VBM)) and tract based spatial fractional anisotropy ((FA) on magnetic resonance imaging (MRI), allowing examination of the neural correlates of apathy and disinhibition. The patients with bvFTD had predominant grey matter loss and corresponding white matter fractional anisotropy reduction in the frontal and temporal lobe compared to the controls. Grey matter loss in frontal, temporal and limbic structures correlated with apathy and degeneration in temporal limbic brain areas correlated with disinhibition. FA changes in inferior fronto-occipital fasciculus and forceps minor correlated with apathy and fibre integrity changes in the superior longitudinal fasciculus correlated with disinhibition. The current study suggests that apathy and disinhibition arises due to changes in the frontal, temporal and limbic brain areas in bvFTD. |
| Author | Mathuranath, Pavagada S. Kesavadas, Chandrasekharan Verghese, Joe Sheelakumari, Raghavan Varghese, Tinu Bineesh, Cheminnikara |
| AuthorAffiliation | 1 Cognition and Behavioural Neurology Section, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, India 2 Department of Neurology, Maulana Hospital, Perinthalmanna, Kerala, India 3 Department of Electronics and Instrumentation, Noorul Islam University, Kumaracoil, Thuckalay, Tamilnadu, India 4 Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, India 6 Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India 5 Integrated Divisions of Cognitive and Motor Aging (Neurology) and Geriatrics (Medicine), Albert Einstein College of Medicine, Bronx, NY, USA |
| AuthorAffiliation_xml | – name: 2 Department of Neurology, Maulana Hospital, Perinthalmanna, Kerala, India – name: 3 Department of Electronics and Instrumentation, Noorul Islam University, Kumaracoil, Thuckalay, Tamilnadu, India – name: 1 Cognition and Behavioural Neurology Section, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, India – name: 6 Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India – name: 4 Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum, India – name: 5 Integrated Divisions of Cognitive and Motor Aging (Neurology) and Geriatrics (Medicine), Albert Einstein College of Medicine, Bronx, NY, USA |
| Author_xml | – sequence: 1 givenname: Raghavan surname: Sheelakumari fullname: Sheelakumari, Raghavan organization: Cognition and Behavioural Neurology Section, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) – sequence: 2 givenname: Cheminnikara surname: Bineesh fullname: Bineesh, Cheminnikara organization: Department of Neurology, Maulana Hospital – sequence: 3 givenname: Tinu surname: Varghese fullname: Varghese, Tinu organization: Department of Electronics and Instrumentation, Noorul Islam University – sequence: 4 givenname: Chandrasekharan surname: Kesavadas fullname: Kesavadas, Chandrasekharan organization: Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST) – sequence: 5 givenname: Joe surname: Verghese fullname: Verghese, Joe organization: Integrated Divisions of Cognitive and Motor Aging (Neurology) and Geriatrics (Medicine), Albert Einstein College of Medicine – sequence: 6 givenname: Pavagada S. surname: Mathuranath fullname: Mathuranath, Pavagada S. email: psmathu@yahoo.com organization: Cognition and Behavioural Neurology Section, Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS) |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31273672$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kU1vFSEYhYlpYz_0D7gwk7hxM5VvZjYmplHbpLEbXZN3gOmlmYErMDfpv5fxttV20RUEnnM4vOcEHYQYHELvCD4jGKtPmRDZ0RaTvsWYCNyyV-iY9Iy0Skhx8LgX6gid5HyLseBdT16jI0aoYlLRY-R-uCVFCFDi7A1MjYkpuQmKy00cG9hC2dw1EGxjffZh4wdffAyND83gNrDzcUlVtYPkIZRmTDGUWNy8jeuxdbMLxcMbdDjClN3b-_UU_fr29ef5RXt1_f3y_MtVa7jipQVregyqH52UAqzFvAdmVAcjGTh2ElthFO16oNxaSwQ3wGFghAiQXS8VO0Wf977bZZidNfXxGkNvk58h3ekIXj-9CX6jb-JOy55TyleDj_cGKf5eXC569tm4aYLg4pI1pYJRVceOK_rhGXpbZxHq91aKdJIpRSr1_v9Ej1EeGqhAtwdMijknN2rjC6wzrgH9pAnWa9l6X7auZeu_ZWtWpfSZ9MH9RRHbi3KFw41L_2K_oPoDi8m-uw |
| CitedBy_id | crossref_primary_10_1007_s40263_021_00854_5 crossref_primary_10_1093_brain_awae067 crossref_primary_10_1093_brain_awac043 crossref_primary_10_3389_fneur_2021_713388 crossref_primary_10_3233_JAD_190884 crossref_primary_10_3233_JAD_221171 crossref_primary_10_1016_j_cortex_2021_06_016 crossref_primary_10_12677_ACM_2023_13112532 crossref_primary_10_1111_ene_14465 crossref_primary_10_1007_s00415_023_11713_2 crossref_primary_10_1162_netn_a_00285 crossref_primary_10_3389_fneur_2024_1345756 crossref_primary_10_1093_brain_awac339 crossref_primary_10_1007_s11682_023_00812_3 crossref_primary_10_1093_braincomms_fcac344 crossref_primary_10_1093_braincomms_fcae123 crossref_primary_10_3390_jpm11070679 crossref_primary_10_1093_brain_awac133 crossref_primary_10_1212_WNL_0000000000207200 crossref_primary_10_1186_s41983_022_00538_x crossref_primary_10_12688_f1000research_20330_1 crossref_primary_10_1097_WNN_0000000000000345 crossref_primary_10_1016_j_neurobiolaging_2023_01_004 crossref_primary_10_3389_fneur_2021_707799 crossref_primary_10_24075_brsmu_2020_075 crossref_primary_10_3233_JAD_220173 crossref_primary_10_3390_geriatrics8020038 crossref_primary_10_3390_ijms22094440 crossref_primary_10_3390_ijms241411732 crossref_primary_10_1007_s11682_024_00913_7 crossref_primary_10_1016_j_nicl_2022_103079 crossref_primary_10_1016_j_cortex_2021_08_015 crossref_primary_10_1002_hbm_26428 crossref_primary_10_1038_s41598_023_35758_5 crossref_primary_10_1016_j_inpsyc_2025_100059 crossref_primary_10_1038_s41598_021_84364_w |
| Cites_doi | 10.1097/WNN.0000000000000044 10.1111/j.1749-6632.1995.tb38127.x 10.1192/bjp.140.6.566 10.1016/j.nlm.2015.03.001 10.1037/a0021681 10.1371/journal.pone.0067457 10.1093/brain/awr173 10.1186/2045-5380-4-4 10.1093/brain/awh628 10.1016/j.psychres.2015.08.041 10.1016/j.neuroimage.2006.02.024 10.1002/gps.1239 10.1093/brain/awl288 10.1159/000091898 10.3233/BEN-2011-0351 10.1093/cercor/bhj043 10.1016/S0166-2236(00)01626-X 10.1212/01.wnl.0000324920.96835.95 10.1017/CBO9780511722110.014 10.1002/ana.20365 10.1016/0022-3956(75)90026-6 10.1002/gps.755 10.1016/j.jalz.2007.04.374 10.1093/brain/awr179 10.3389/fnhum.2015.00611 10.1152/physrev.00002.2003 10.1016/j.neuroimage.2006.12.006 10.1016/S1474-4422(05)70223-4 10.1136/jnnp.70.3.323 10.1001/archneur.64.2.246 10.1159/000194658 10.1016/j.neuroimage.2004.10.023 10.1016/j.neuropsychologia.2010.07.036 10.1001/archneur.58.11.1803 |
| ContentType | Journal Article |
| Copyright | Springer Science+Business Media, LLC, part of Springer Nature 2019 Brain Imaging and Behavior is a copyright of Springer, (2019). All Rights Reserved. |
| Copyright_xml | – notice: Springer Science+Business Media, LLC, part of Springer Nature 2019 – notice: Brain Imaging and Behavior is a copyright of Springer, (2019). All Rights Reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7RV 7TK 7X7 7XB 88E 88G 8FE 8FG 8FH 8FI 8FJ 8FK ABUWG AFKRA ARAPS AZQEC BBNVY BENPR BGLVJ BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. KB0 LK8 M0S M1P M2M M7P NAPCQ P5Z P62 PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS PSYQQ Q9U 7X8 5PM |
| DOI | 10.1007/s11682-019-00150-3 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Proquest Nursing & Allied Health Source Neurosciences Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Psychology Database (Alumni) ProQuest SciTech Collection ProQuest Technology Collection ProQuest Natural Science Collection ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland Advanced Technologies & Aerospace Collection ProQuest Central Essentials Biological Science Collection ProQuest Central Technology Collection Natural Science Collection ProQuest One Community College ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Biological Sciences ProQuest Health & Medical Collection Medical Database Psychology Database Biological Science Database Nursing & Allied Health Premium Advanced Technologies & Aerospace Database ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Premium ProQuest One Academic (New) ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest One Psychology ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest One Psychology ProQuest Central Student Technology Collection ProQuest One Academic Middle East (New) ProQuest Advanced Technologies & Aerospace Collection ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) Advanced Technologies & Aerospace Collection ProQuest Biological Science Collection ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Nursing & Allied Health Source ProQuest Hospital Collection ProQuest Technology Collection Health Research Premium Collection (Alumni) ProQuest Psychology Journals (Alumni) Biological Science Database ProQuest SciTech Collection Neurosciences Abstracts ProQuest Hospital Collection (Alumni) Advanced Technologies & Aerospace Database Nursing & Allied Health Premium ProQuest Health & Medical Complete ProQuest Medical Library ProQuest Psychology Journals ProQuest One Academic UKI Edition ProQuest Nursing & Allied Health Source (Alumni) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE ProQuest One Psychology |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: 8FG name: ProQuest Technology Collection url: https://search.proquest.com/technologycollection1 sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1931-7565 |
| EndPage | 2011 |
| ExternalDocumentID | PMC6942247 31273672 10_1007_s11682_019_00150_3 |
| Genre | Journal Article |
| GrantInformation_xml | – fundername: National Institute on Aging (NIA), USA grantid: R21AG029799 to JV and R01AG039330-01) to PSM – fundername: NIA NIH HHS grantid: R21 AG029799 – fundername: NIA NIH HHS grantid: R01 AG039330 |
| GroupedDBID | --- -55 -5G -BR -EM -Y2 -~C .86 .VR 04C 06D 0R~ 0VY 1N0 203 23N 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2VQ 2~H 30V 3V. 4.4 406 408 409 40D 40E 53G 5GY 5VS 67Z 6J9 6NX 7RV 7X7 875 88E 8FE 8FG 8FH 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AACDK AAHNG AAIAL AAJBT AAJKR AANXM AANZL AARHV AARTL AASML AATNV AATVU AAUYE AAWCG AAYIU AAYQN AAYTO AAYZH ABAKF ABBXA ABDZT ABECU ABFTV ABHLI ABHQN ABIVO ABJNI ABJOX ABKCH ABMNI ABMQK ABNWP ABPLI ABQBU ABSXP ABTEG ABTHY ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACAOD ACDTI ACGFS ACHSB ACHXU ACIWK ACKNC ACMDZ ACMLO ACOKC ACOMO ACPIV ACPRK ACREN ACSNA ACZOJ ADBBV ADHHG ADHIR ADINQ ADKNI ADKPE ADRFC ADTPH ADURQ ADYFF ADYOE ADZKW AEBTG AEFQL AEGAL AEGNC AEJHL AEJRE AEKMD AEMSY AENEX AEOHA AEPYU AESKC AETLH AEVLU AEXYK AFBBN AFGCZ AFKRA AFLOW AFQWF AFRAH AFWTZ AFYQB AFZKB AGAYW AGDGC AGJBK AGMZJ AGQEE AGQMX AGRTI AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHMBA AHSBF AHYZX AIAKS AIGIU AIIXL AILAN AITGF AJBLW AJRNO AJZVZ AKMHD ALIPV ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMTXH AMXSW AMYLF AMYQR AOCGG ARAPS ARMRJ AXYYD AZQEC B-. BA0 BBNVY BDATZ BENPR BGLVJ BGNMA BHPHI BKEYQ BMSDO BPHCQ BSONS BVXVI CAG CCPQU COF CS3 CSCUP DDRTE DNIVK DPUIP DU5 DWQXO EBD EBLON EBS EIHBH EIOEI EJD EMOBN ESBYG EX3 F5P FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA GGCAI GGRSB GJIRD GNUQQ GNWQR GQ6 GQ7 GQ8 GXS H13 HCIFZ HF~ HG5 HG6 HLICF HMCUK HMJXF HQYDN HRMNR HZ~ IJ- IKXTQ IWAJR IXC IXD IXE IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV LK8 LLZTM M1P M2M M4Y M7P MA- NAPCQ NPVJJ NQJWS NU0 O9- O93 O9J OAM P62 P9L PF0 PQQKQ PROAC PSQYO PSYQQ PT4 QOR QOS R89 R9I ROL RPX RSV S16 S1Z S27 S3B SAP SBS SDH SHX SISQX SJYHP SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZN T13 TSG TSK TSV TUC U2A U9L UG4 UKHRP UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WK8 WOW YLTOR Z45 Z82 Z83 ZMTXR ZOVNA ~A9 ~KM AAPKM AAYXX ABBRH ABDBE ABFSG ACMFV ACSTC AEZWR AFDZB AFHIU AFOHR AHPBZ AHWEU AIXLP ATHPR AYFIA CITATION PHGZM PHGZT CGR CUY CVF ECM EIF NPM 7TK 7XB 8FK ABRTQ K9. PJZUB PKEHL PPXIY PQEST PQGLB PQUKI PRINS Q9U 7X8 PUEGO 5PM |
| ID | FETCH-LOGICAL-c474t-adc90a79fe665add049a3c78af1b40e60d5c7289a24ddd154ca4ab3115a689673 |
| IEDL.DBID | 8FG |
| ISSN | 1931-7557 1931-7565 |
| IngestDate | Thu Aug 21 18:13:29 EDT 2025 Thu Sep 04 23:50:39 EDT 2025 Fri Jul 25 11:01:26 EDT 2025 Wed Feb 19 02:28:00 EST 2025 Tue Jul 01 04:04:32 EDT 2025 Thu Apr 24 23:00:54 EDT 2025 Fri Feb 21 02:37:09 EST 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 5 |
| Keywords | Fractional anisotropy Frontal system Behavioral scale Behavioral variant FTD Inferior fronto-occipital fasciculus |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c474t-adc90a79fe665add049a3c78af1b40e60d5c7289a24ddd154ca4ab3115a689673 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/6942247 |
| PMID | 31273672 |
| PQID | 2251863771 |
| PQPubID | 1486349 |
| PageCount | 8 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_6942247 proquest_miscellaneous_2253271680 proquest_journals_2251863771 pubmed_primary_31273672 crossref_citationtrail_10_1007_s11682_019_00150_3 crossref_primary_10_1007_s11682_019_00150_3 springer_journals_10_1007_s11682_019_00150_3 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2020-10-01 |
| PublicationDateYYYYMMDD | 2020-10-01 |
| PublicationDate_xml | – month: 10 year: 2020 text: 2020-10-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | New York |
| PublicationPlace_xml | – name: New York – name: United States – name: Indianapolis |
| PublicationTitle | Brain imaging and behavior |
| PublicationTitleAbbrev | Brain Imaging and Behavior |
| PublicationTitleAlternate | Brain Imaging Behav |
| PublicationYear | 2020 |
| Publisher | Springer US Springer Nature B.V |
| Publisher_xml | – name: Springer US – name: Springer Nature B.V |
| References | Le Ber, Guedj, Gabelle, Verpillat, Volteau, Thomas-Anterion (CR14) 2006; 129 Sah, Faber, Lopez De Armentia, Power (CR28) 2003; 83 Brown, Pluck (CR4) 2000; 23 CR18 Rascovsky, Hodges, Knopman, Mendez, Kramer, Neuhaus, van Swieten, Seelaar, Dopper, Onyike, Hillis, Josephs, Boeve, Kertesz, Seeley, Rankin, Johnson, Gorno-Tempini, Rosen, Prioleau-Latham, Lee, Kipps, Lillo, Piguet, Rohrer, Rossor, Warren, Fox, Galasko, Salmon, Black, Mesulam, Weintraub, Dickerson, Diehl-Schmid, Pasquier, Deramecourt, Lebert, Pijnenburg, Chow, Manes, Grafman, Cappa, Freedman, Grossman, Miller (CR25) 2011; 134 Walters, Kiehl (CR31) 2015; 230 Peters, Perani, Herholz, Holthoff, Beuthien-Baumann, Sorbi, Pupi, Degueldre, Lemaire, Collette, Salmon (CR23) 2006; 21 CR33 CR30 Zamboni, Huey, Krueger, Nichelli, Grafman (CR34) 2008; 71 Kumfor, Irish, Hodges, Piguet (CR13) 2013; 8 Malloy, Tremont, Grace, Frakey (CR17) 2007; 3 Powers, Massimo, McMillan, Yushkevich, Zhang, Gee, Grossman (CR24) 2014; 27 Hughes, Berg, Danziger, Coben, Martin (CR11) 1982; 140 Robert, Clairet, Benoit, Koutaich, Bertogliati, Tible, Caci, Borg, Brocker, Bedoucha (CR26) 2002; 17 Massimo, Powers, Evans, McMillan, Rascovsky, Eslinger, Ersek, Irwin, Grossman (CR19) 2015; 9 CR3 Cummings (CR5) 1995; 769 Bakchine, Bogousslavsky, Cummings (CR2) 2000 CR9 Folstein, Folstein, McHugh (CR7) 1975; 12 CR21 Rosen, Allison, Schauer, Gorno-Tempini, Weiner, Miller (CR27) 2005; 128 Franceschi, Anchisi, Pelati, Zuffi, Matarrese, Moresco, Fazio, Perani (CR8) 2005; 57 Neary, Snowden, Mann (CR22) 2005; 4 Krueger, Laluz, Rosen, Neuhaus, Miller, Kramer (CR12) 2011; 25 Whitwell, Sampson, Loy, Warren, Rossor, Fox, Warren (CR32) 2007; 35 Baeuchl, Meyer, Hoppstädter, Diener, Flor (CR1) 2015; 121 Mathuranath, Hodges, Mathew, Cherian, George, Bak (CR20) 2004; 19 Hornberger, Geng, Hodges (CR10) 2011; 134 Levita, Bois, Healey, Smyllie, Papakonstantinou, Hartley, Lever (CR15) 2014; 4 Levy, Dubois (CR16) 2006; 16 Smith, Jenkinson, Johansen-Berg, Rueckert, Nichols, Mackay, Watkins, Ciccarelli, Cader, Matthews, Behrens (CR29) 2006; 31 Eslinger, Moore, Antani, Anderson, Grossman (CR6) 2012; 25 PH Robert (150_CR26) 2002; 17 L Levita (150_CR15) 2014; 4 150_CR21 C Baeuchl (150_CR1) 2015; 121 RG Brown (150_CR4) 2000; 23 L Massimo (150_CR19) 2015; 9 R Levy (150_CR16) 2006; 16 150_CR30 JL Cummings (150_CR5) 1995; 769 M Franceschi (150_CR8) 2005; 57 150_CR3 HJ Rosen (150_CR27) 2005; 128 MF Folstein (150_CR7) 1975; 12 JL Whitwell (150_CR32) 2007; 35 150_CR33 150_CR9 PS Mathuranath (150_CR20) 2004; 19 GD Walters (150_CR31) 2015; 230 PJ Eslinger (150_CR6) 2012; 25 CE Krueger (150_CR12) 2011; 25 SM Smith (150_CR29) 2006; 31 P Malloy (150_CR17) 2007; 3 M Hornberger (150_CR10) 2011; 134 F Kumfor (150_CR13) 2013; 8 I Le Ber (150_CR14) 2006; 129 150_CR18 S Bakchine (150_CR2) 2000 CP Hughes (150_CR11) 1982; 140 JP Powers (150_CR24) 2014; 27 D Neary (150_CR22) 2005; 4 F Peters (150_CR23) 2006; 21 K Rascovsky (150_CR25) 2011; 134 P Sah (150_CR28) 2003; 83 G Zamboni (150_CR34) 2008; 71 |
| References_xml | – volume: 27 start-page: 206 issue: 4 year: 2014 end-page: 214 ident: CR24 article-title: White matter disease contributes to apathy and disinhibition in behavioral variant frontotemporal dementia publication-title: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology doi: 10.1097/WNN.0000000000000044 – ident: CR18 – volume: 769 start-page: 1 year: 1995 end-page: 13 ident: CR5 article-title: Anatomic and behavioral aspects of frontal-subcortical circuits publication-title: Annals of the New York Academy of Sciences doi: 10.1111/j.1749-6632.1995.tb38127.x – volume: 140 start-page: 566 year: 1982 end-page: 572 ident: CR11 article-title: A new clinical scale for the staging of dementia publication-title: The British Journal of Psychiatry doi: 10.1192/bjp.140.6.566 – ident: CR30 – volume: 121 start-page: 1 year: 2015 end-page: 11 ident: CR1 article-title: Contextual fear conditioning in humans using feature-identical contexts publication-title: Neurobiology of Learning and Memory doi: 10.1016/j.nlm.2015.03.001 – volume: 25 start-page: 249 issue: 2 year: 2011 end-page: 259 ident: CR12 article-title: Double dissociation in the anatomy of socioemotional disinhibition and executive functioning in dementia publication-title: Neuropsychology doi: 10.1037/a0021681 – volume: 8 issue: 6 year: 2013 ident: CR13 article-title: Discrete neural correlates for the recognition of negative emotions: Insights from frontotemporal dementia publication-title: PLoS One doi: 10.1371/journal.pone.0067457 – ident: CR33 – volume: 134 start-page: 2502 issue: Pt 9 year: 2011 end-page: 2512 ident: CR10 article-title: Convergent grey and white matter evidence of orbitofrontal cortex changes related to disinhibition in behavioural variant frontotemporal dementia publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awr173 – volume: 4 start-page: 4 issue: 1 year: 2014 ident: CR15 article-title: The Behavioural inhibition system, anxiety and hippocampal volume in a non-clinical population publication-title: Biology of Mood & Anxiety Disorders doi: 10.1186/2045-5380-4-4 – volume: 128 start-page: 2612 issue: Pt 11 year: 2005 end-page: 2625 ident: CR27 article-title: Neuroanatomical correlates of behavioural disorders in dementia publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awh628 – volume: 230 start-page: 205 issue: 2 year: 2015 end-page: 210 ident: CR31 article-title: Limbic correlates of fearlessness and disinhibition in incarcerated youth: Exploring the brain-behavior relationship with the psychopathy checklist: Youth version publication-title: Psychiatry Research doi: 10.1016/j.psychres.2015.08.041 – volume: 31 start-page: 1487 issue: 4 year: 2006 end-page: 1505 ident: CR29 article-title: Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data publication-title: NeuroImage doi: 10.1016/j.neuroimage.2006.02.024 – ident: CR21 – volume: 19 start-page: 1 year: 2004 end-page: 7 ident: CR20 article-title: Adaptation of the ACE for a Malayalam speaking population in southern India publication-title: International Journal of Geriatric Psychiatry doi: 10.1002/gps.1239 – volume: 129 start-page: 3051 issue: Pt 11 year: 2006 end-page: 3065 ident: CR14 article-title: Demographic, neurological and behavioural characteristics and brain perfusion SPECT in frontal variant of frontotemporal dementia publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awl288 – volume: 21 start-page: 373 issue: 5–6 year: 2006 end-page: 379 ident: CR23 article-title: Orbitofrontal dysfunction related to both apathy and disinhibition in frontotemporal dementia publication-title: Dementia and Geriatric Cognitive Disorders doi: 10.1159/000091898 – volume: 25 start-page: 127 issue: 2 year: 2012 end-page: 136 ident: CR6 article-title: Apathy in frontotemporal dementia: Behavioral and neuroimaging correlates publication-title: Behavioural Neurology doi: 10.3233/BEN-2011-0351 – volume: 16 start-page: 916 issue: 7 year: 2006 end-page: 928 ident: CR16 article-title: Apathy and the functional anatomy of the prefrontal cortex-basal ganglia circuits publication-title: Cerebral Cortex (New York, N.Y.: 1991) doi: 10.1093/cercor/bhj043 – volume: 23 start-page: 412 issue: 9 year: 2000 end-page: 417 ident: CR4 article-title: Negative symptoms: The “pathology” of motivation and goal-directed behaviour publication-title: Trends in Neurosciences doi: 10.1016/S0166-2236(00)01626-X – ident: CR3 – volume: 71 start-page: 736 issue: 10 year: 2008 end-page: 742 ident: CR34 article-title: Apathy and disinhibition in frontotemporal dementia: Insights into their neural correlates publication-title: Neurology doi: 10.1212/01.wnl.0000324920.96835.95 – start-page: 369 year: 2000 end-page: 398 ident: CR2 article-title: Temporal lobe behavioral syndromes publication-title: Behavior and Mood Disorders in Focal Brain Lesions doi: 10.1017/CBO9780511722110.014 – volume: 57 start-page: 216 issue: 2 year: 2005 end-page: 225 ident: CR8 article-title: Glucose metabolism and serotonin receptors in the frontotemporal lobe degeneration publication-title: Annals of Neurology doi: 10.1002/ana.20365 – ident: CR9 – volume: 12 start-page: 189 issue: 3 year: 1975 end-page: 198 ident: CR7 article-title: Mini-mental state.° a practical method for grading the cognitive state of patients for the clinician publication-title: Journal of Psychiatric Research doi: 10.1016/0022-3956(75)90026-6 – volume: 17 start-page: 1099 issue: 12 year: 2002 end-page: 1105 ident: CR26 article-title: The apathy inventory: Assessment of apathy and awareness in Alzheimer’s disease, Parkinson’s disease and mild cognitive impairment publication-title: International Journal of Geriatric Psychiatry doi: 10.1002/gps.755 – volume: 3 start-page: 200 issue: 3 year: 2007 end-page: 203 ident: CR17 article-title: The frontal systems behavior scale discriminates frontotemporal dementia from Alzheimer’s disease publication-title: Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association doi: 10.1016/j.jalz.2007.04.374 – volume: 134 start-page: 2456 issue: Pt 9 year: 2011 end-page: 2477 ident: CR25 article-title: Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awr179 – volume: 9 start-page: 611 year: 2015 ident: CR19 article-title: Apathy in frontotemporal degeneration: Neuroanatomical evidence of impaired goal-directed behavior publication-title: Frontiers in Human Neuroscience doi: 10.3389/fnhum.2015.00611 – volume: 83 start-page: 803 issue: 3 year: 2003 end-page: 834 ident: CR28 article-title: The amygdaloid complex: Anatomy and physiology publication-title: Physiological Reviews doi: 10.1152/physrev.00002.2003 – volume: 35 start-page: 207 issue: 1 year: 2007 end-page: 213 ident: CR32 article-title: VBM signatures of abnormal eating behaviours in frontotemporal lobar degeneration publication-title: NeuroImage doi: 10.1016/j.neuroimage.2006.12.006 – volume: 4 start-page: 771 issue: 11 year: 2005 end-page: 780 ident: CR22 article-title: Frontotemporal dementia publication-title: The Lancet Neurology doi: 10.1016/S1474-4422(05)70223-4 – volume: 21 start-page: 373 issue: 5–6 year: 2006 ident: 150_CR23 publication-title: Dementia and Geriatric Cognitive Disorders doi: 10.1159/000091898 – ident: 150_CR30 doi: 10.1136/jnnp.70.3.323 – volume: 35 start-page: 207 issue: 1 year: 2007 ident: 150_CR32 publication-title: NeuroImage doi: 10.1016/j.neuroimage.2006.12.006 – volume: 25 start-page: 127 issue: 2 year: 2012 ident: 150_CR6 publication-title: Behavioural Neurology doi: 10.3233/BEN-2011-0351 – volume: 27 start-page: 206 issue: 4 year: 2014 ident: 150_CR24 publication-title: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology doi: 10.1097/WNN.0000000000000044 – start-page: 369 volume-title: Behavior and Mood Disorders in Focal Brain Lesions year: 2000 ident: 150_CR2 doi: 10.1017/CBO9780511722110.014 – volume: 140 start-page: 566 year: 1982 ident: 150_CR11 publication-title: The British Journal of Psychiatry doi: 10.1192/bjp.140.6.566 – volume: 19 start-page: 1 year: 2004 ident: 150_CR20 publication-title: International Journal of Geriatric Psychiatry doi: 10.1002/gps.1239 – ident: 150_CR3 doi: 10.1001/archneur.64.2.246 – volume: 129 start-page: 3051 issue: Pt 11 year: 2006 ident: 150_CR14 publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awl288 – volume: 57 start-page: 216 issue: 2 year: 2005 ident: 150_CR8 publication-title: Annals of Neurology doi: 10.1002/ana.20365 – volume: 134 start-page: 2456 issue: Pt 9 year: 2011 ident: 150_CR25 publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awr179 – volume: 4 start-page: 4 issue: 1 year: 2014 ident: 150_CR15 publication-title: Biology of Mood & Anxiety Disorders doi: 10.1186/2045-5380-4-4 – volume: 9 start-page: 611 year: 2015 ident: 150_CR19 publication-title: Frontiers in Human Neuroscience doi: 10.3389/fnhum.2015.00611 – volume: 12 start-page: 189 issue: 3 year: 1975 ident: 150_CR7 publication-title: Journal of Psychiatric Research doi: 10.1016/0022-3956(75)90026-6 – ident: 150_CR18 doi: 10.1159/000194658 – volume: 8 issue: 6 year: 2013 ident: 150_CR13 publication-title: PLoS One doi: 10.1371/journal.pone.0067457 – volume: 71 start-page: 736 issue: 10 year: 2008 ident: 150_CR34 publication-title: Neurology doi: 10.1212/01.wnl.0000324920.96835.95 – volume: 83 start-page: 803 issue: 3 year: 2003 ident: 150_CR28 publication-title: Physiological Reviews doi: 10.1152/physrev.00002.2003 – volume: 134 start-page: 2502 issue: Pt 9 year: 2011 ident: 150_CR10 publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awr173 – volume: 23 start-page: 412 issue: 9 year: 2000 ident: 150_CR4 publication-title: Trends in Neurosciences doi: 10.1016/S0166-2236(00)01626-X – volume: 4 start-page: 771 issue: 11 year: 2005 ident: 150_CR22 publication-title: The Lancet Neurology doi: 10.1016/S1474-4422(05)70223-4 – volume: 16 start-page: 916 issue: 7 year: 2006 ident: 150_CR16 publication-title: Cerebral Cortex (New York, N.Y.: 1991) doi: 10.1093/cercor/bhj043 – volume: 128 start-page: 2612 issue: Pt 11 year: 2005 ident: 150_CR27 publication-title: Brain: A Journal of Neurology doi: 10.1093/brain/awh628 – volume: 121 start-page: 1 year: 2015 ident: 150_CR1 publication-title: Neurobiology of Learning and Memory doi: 10.1016/j.nlm.2015.03.001 – ident: 150_CR33 doi: 10.1016/j.neuroimage.2004.10.023 – ident: 150_CR9 doi: 10.1016/j.neuropsychologia.2010.07.036 – volume: 31 start-page: 1487 issue: 4 year: 2006 ident: 150_CR29 publication-title: NeuroImage doi: 10.1016/j.neuroimage.2006.02.024 – volume: 230 start-page: 205 issue: 2 year: 2015 ident: 150_CR31 publication-title: Psychiatry Research doi: 10.1016/j.psychres.2015.08.041 – volume: 25 start-page: 249 issue: 2 year: 2011 ident: 150_CR12 publication-title: Neuropsychology doi: 10.1037/a0021681 – ident: 150_CR21 doi: 10.1001/archneur.58.11.1803 – volume: 17 start-page: 1099 issue: 12 year: 2002 ident: 150_CR26 publication-title: International Journal of Geriatric Psychiatry doi: 10.1002/gps.755 – volume: 3 start-page: 200 issue: 3 year: 2007 ident: 150_CR17 publication-title: Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association doi: 10.1016/j.jalz.2007.04.374 – volume: 769 start-page: 1 year: 1995 ident: 150_CR5 publication-title: Annals of the New York Academy of Sciences doi: 10.1111/j.1749-6632.1995.tb38127.x |
| SSID | ssj0054891 |
| Score | 2.3944044 |
| Snippet | Neuroanatomical correlates of apathy and disinhibition, behavioral abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remain unclear. In this... Neuroanatomical correlates of apathy and disinhibition, behavioural abnormalities in behavioral variant Frontotemporal dementia (bvFTD) remains unclear. In... |
| SourceID | pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 2004 |
| SubjectTerms | Abnormalities Anatomy Anisotropy Apathy Behavior rating scales Biomedical and Life Sciences Biomedicine Brain Brain - diagnostic imaging Brain - pathology Brain - physiopathology Brain architecture Correlation analysis Cortex Degeneration Dementia Dementia disorders Emotional behavior Female Frontotemporal dementia Frontotemporal Dementia - diagnostic imaging Frontotemporal Dementia - pathology Frontotemporal Dementia - physiopathology Frontotemporal Dementia - psychology Humans Magnetic Resonance Imaging Male Medical instruments Middle Aged Morphometry Neurodegeneration Neuroimaging Neuropsychological Tests Neuropsychology Neuroradiology Neurosciences NMR Nuclear magnetic resonance Original Research Psychiatry Substantia alba Substantia grisea Temporal lobe |
| SummonAdditionalLinks | – databaseName: SpringerLINK - Czech Republic Consortium dbid: AGYKE link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LbxMxEB5BKiEu5Q0LBRmJG7jah9ePY4VaKlA5EamcVn6tumrkIJJUgl_P2PEmSgtIPXvW68fY_sae-QbgnWVNz7yrqauloQxtCKq4c7Qtm1oYUxqpYzTy2Vd-OmWfz9vzHBS2GL3dxyfJtFNvg90qLqMbgaKJF482d2GvraSSE9g7-vT9y_G4AyMIT5nyEJtUVLStyMEyf69l90C6gTJvOkteezFNB9HJA5iOXVj7n1werpbm0P6-xu542z4-hP2MTMnRWpUewR0fHsO9s_z2_gR84vHQAa30RDFAbEzsMYtYlcx7omNu419EB0fcsBjCxWCSNxgZAslcAJHhg1yhcY6zSfrEnJCZsWbEpWvKQT-F6cnxt4-nNCdpoJYJtqTaWVVqoXrPeYubJVocurFC6r4yrPS8dK0VaNXpmjnnELBZzbSJHD-aS8VF8wwmYR78CyBWeRT2XHqsufVMObTlNFaAKNQYVxZQjTPV2cxgHhNpzLot93Icvw7Hr0vj1zUFvN9882PN3_Ff6YNRAbq8lhcd7niV5I0QVQFvN8W4CuPTig5-vkoyqNtYHTby-VpfNr9rKoSIXNQFiB1N2ghEhu_dkjBcJKZvrhhCLFHAh1Fdts36dy9e3k78Fdyv4yVC8lA8gMny58q_RqS1NG_ywvoDYiwgXg priority: 102 providerName: Springer Nature |
| Title | Neuroanatomical correlates of apathy and disinhibition in behavioural variant frontotemporal dementia |
| URI | https://link.springer.com/article/10.1007/s11682-019-00150-3 https://www.ncbi.nlm.nih.gov/pubmed/31273672 https://www.proquest.com/docview/2251863771 https://www.proquest.com/docview/2253271680 https://pubmed.ncbi.nlm.nih.gov/PMC6942247 |
| Volume | 14 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1ba9swFD70AmMvY1t3cdcGDfq2ifkiS_bTyErS0tFSygLZk9HN1BCUbkkL-_c7UuSErKxPBkuWJZ0j6TvS0XcATjQrWmZNTk1eKcrQhqA1N4aWaZELpVJVSX8b-fKKn0_YxbScxg23RXSr7OfEMFGbufZ75F9Q77KKF0JkX-9-UR81yp-uxhAau7Cf4Urj9bwan_UzMYLxEDEPMUpGRVmKeGlmdXUu45V3SqhpYNmjxfbC9AhtPnaa_OfkNCxI45fwIiJJMlyJ_hXsWPcanl3Gs_IDsIF3Qzq0qgMlANE-EMfMY0syb4n0sYj_EOkMMd2ic7edCt5bpHMk3t33jBzkAY1p7H3SBqaDyGQ1IyZsK3byDUzGox-n5zQGVaCaCbak0ug6laJuLeclTm5oIchCi0q2mWKp5akptUArTObMGIMAS0smlefkkbyquSjewp6bO_seiK4tZra8slhyaVlt0PaSWACiRqVMmkDW92ijI-O4D3wxazZcyV4KDUqhCVJoigQ-rb-5W_FtPJn7qBdUE8feotloSgIf18k4avxRiHR2fh_yoC5icVjJdyu5rn9XZAjpuMgTEFsSX2fwjNzbKa67DczcvGYIiUQCn3vd2FTr_604fLoVH-B57o384EF4BHvL3_f2GJHQUg1gV0zFICj9APaHZz-_j_D5bXR1fYNvJ_nwL6IQC4A |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VrQRcKp5tSgEjwQks8nDs5IAQj1Zb2l0h1Eq9Bb-iRlplS3db1D_Fb2TsOLtaKnrr2Y5je8b2N_bMNwCvNctqZk1KTVooytCGoCU3huZxlgqlYlVIF408GvPhMft2kp-swZ8-Fsa5VfZ7ot-ozVS7O_L3qHdJwTMhko9nv6jLGuVeV_sUGp1aHNir32iyzT7sf0X5vknTvd2jL0MasgpQzQSbU2l0GUtR1pbzHFc3QmSZaVHIOlEstjw2uRZohsiUGWMQYWjJpHKkNJIXJRcZtnsH1pmLaB3A-ufd8fcf_d6P8N_n6ENUlFCR5yKE6XTBegkvnBtEST2vH81Wj8Jr-Pa6m-Y_b7X-CNx7ABsBu5JPnbI9hDXbPoK7o_A6_xisZ_qQLdrxnoSAaJf6Y-LQLJnWRLrsx1dEtoaYZta0p43y_mKkaUlgC3AcIOQSzXeUN6k9t0LgzpoQ4y8yG_kEjm9lwp_CoJ22dguILi1Wtryw2HJuWWnQ2pPYAOJUpUwcQdLPaKUDx7lLtTGpluzMTgoVSqHyUqiyCN4uvjnrGD5urL3TC6oKq31WLXUzgleLYlyn7vFFtnZ64eug9mNz2MnNTq6L32UJgkgu0gjEisQXFRwH-GpJ25x6LnBeMgRhIoJ3vW4su_X_UWzfPIqXcG94NDqsDvfHB8_gfuquGLz_4g4M5ucX9jnisLl6EZSfwM_bXm9_ARjcRVc |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwEB6VIlVcEG9SChgJTmA1iR07OSCEKKuW0ooDlfYW_IoaaeUt7Laof41fx9h5rJaK3nq249ieGfsbe_wNwGvDWcOdzanNS005-hC0EtbSImW51DrVpQqvkY-Oxf4J_zItphvwZ3gLE8IqhzUxLtR2bsIZ-S7qXVYKJmW22_RhEd_2Jh_OftKQQSrctA7pNDoVOXSXv9F9W7w_2ENZv8nzyefvn_Zpn2GAGi75kiprqlTJqnFCFGjpCJcVM7JUTaZ56kRqCyPRJVE5t9Yi2jCKKx0IapQoKyEZtnsLbkuGqAptSU5HZw8dgZitD_FRRmVRyP7BTvdsLxNlCIioaGT4o2x9U7yCdK8GbP5zaxs3w8k9uNujWPKxU7v7sOH8A9g66u_pH4KLnB_Ko0cf6QiICUlAZgHXknlDVMiDfEmUt8S2i9aftjpGjpHWk543ILCBkAt05FHypIksCz2L1ozYeKTZqkdwciPT_Rg2_dy7p0BM5bCyE6XDlgvHK4t-n8IGELFqbdMEsmFGa9OznYekG7N6xdMcpFCjFOoohZol8Hb85qzj-ri29s4gqLq3-0W90tIEXo3FaLHhGkZ5Nz-PddAOsDns5JNOruPvWIZwUsg8Abkm8bFCYANfL_HtaWQFFxVHOCYTeDfoxqpb_x_F9vWjeAlbaGX114Pjw2dwJw9nDTGQcQc2l7_O3XMEZEv9Imo-gR83bWp_AYl0SB4 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Neuroanatomical+correlates+of+Apathy+and+Disinhibition+in+behavioural+variant+Frontotemporal+dementia&rft.jtitle=Brain+imaging+and+behavior&rft.au=R%2C+Sheelakumari&rft.au=C%2C+Bineesh&rft.au=Varghese%2C+Tinu&rft.au=Kesavadas%2C+C.&rft.date=2020-10-01&rft.issn=1931-7557&rft.eissn=1931-7565&rft.volume=14&rft.issue=5&rft.spage=2004&rft.epage=2011&rft_id=info:doi/10.1007%2Fs11682-019-00150-3&rft_id=info%3Apmid%2F31273672&rft.externalDocID=PMC6942247 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1931-7557&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1931-7557&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1931-7557&client=summon |