Prevention and management of secondary central nervous system lymphoma

• Published in: Haematologica (Roma) Vol. 108; no. 3; pp. 673 - 689
• Main Authors: Bobillo, Sabela, Khwaja, Jahanzaib, Ferreri, Andrés J.M., Cwynarski, Kate
• Format: Journal Article
• Language: English
• Published: Italy Fondazione Ferrata Storti 01.03.2023; Ferrata Storti Foundation
• Subjects: Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Central Nervous System - pathology; Central Nervous System Neoplasms - diagnosis; Central Nervous System Neoplasms - etiology; Central Nervous System Neoplasms - prevention & control; Humans; Lymphoma, Large B-Cell, Diffuse - drug therapy; Lymphoma, Large B-Cell, Diffuse - therapy; Methotrexate - therapeutic use; Neoplasm Recurrence, Local - drug therapy; Prospective Studies; Retrospective Studies; Review

Secondary central nervous system (CNS) lymphoma (SCNSL) is defined by the involvement of the CNS, either at the time of initial diagnosis of systemic lymphoma or in the setting of relapse, and can be either isolated or with synchronous systemic disease. The risk of CNS involvement in patients with d...