Roles of two glutathione S-transferases in the final step of the β-aryl ether cleavage pathway in Sphingobium sp. strain SYK-6

• Published in: Scientific reports Vol. 10; no. 1; p. 20614
• Main Authors: Higuchi, Yudai, Sato, Daisuke, Kamimura, Naofumi, Masai, Eiji
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 26.11.2020; Nature Publishing Group
• Subjects: 631/326/2522; 631/326/41/1969; 631/443/319; 631/45/607/1172; Aromatic compounds; Bacterial Proteins - metabolism; Carbon; Catalysis; Dehydrogenases; Enantiomers; Enzymes; Ether - metabolism; Genes; Glutathione; Glutathione - metabolism; Glutathione Transferase - metabolism; Guaiacol; Humanities and Social Sciences; Lignin; Lignin - metabolism; multidisciplinary; Oxidation; Oxidation-Reduction; Science; Science (multidisciplinary); Sphingobium; Sphingomonadaceae - metabolism; Stereoisomerism; Stereoisomers; Substrate Specificity - physiology; Syk protein

Sphingobium sp. strain SYK-6 is an alphaproteobacterial degrader of lignin-derived aromatic compounds, which can degrade all the stereoisomers of β-aryl ether-type compounds. SYK-6 cells convert four stereoisomers of guaiacylglycerol-β-guaiacyl ether (GGE) into two enantiomers of α-(2-methoxyphenoxy...