Role of a schistosoma haematobium specific microRNA as a predictive and prognostic tool for bilharzial bladder cancer in Egypt

• Published in: Scientific reports Vol. 10; no. 1; p. 18844
• Main Authors: Gaber, Dalia A., Wassef, Rita M., El-Ayat, Wael M., El-Moazen, Mohamed I., Montasser, Karim A., Swar, Sherif A., Amin, Hebat Allah A.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 02.11.2020; Nature Publishing Group
• Subjects: 631/337; 631/67; 692/4017; 692/4025; 692/53; Animals; Biomarkers; Biomarkers, Tumor - urine; Bladder cancer; Cancer; Cystitis; Diagnosis; Egypt; Gene expression; Hemagglutination; Hemagglutination Tests - methods; Humanities and Social Sciences; Indirect hemagglutination; Kinases; Malignancy; MAP kinase; MAP Kinase Kinase 3 - urine; MicroRNAs; MicroRNAs - urine; miRNA; multidisciplinary; Predictive Value of Tests; Prognosis; Protein kinase; Schistosoma haematobium - genetics; Schistosomiasis haematobia - complications; Schistosomiasis haematobia - diagnosis; Science; Science (multidisciplinary); Urinary bladder; Urinary Bladder Neoplasms - diagnosis; Urinary Bladder Neoplasms - etiology; Egypt

Urinary bladder cancer is a common malignancy in Egypt, thus reliable methodologies are required for screening and early detection. In this study, we analyzed the gene expression of a Schistosoma hematobium specific microRNA “ Sha-miR-71a ” and mitogen-associated protein kinase-3 (MAPK-3) in the uri...