Nonalcoholic Liver Disease in Children and Adolescents

Pediatric nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in children. The spectrum of NAFLD ranges from steatosis to nonalcoholic steatohepatitis (NASH) to fibrosis. Obesity rates in children continue to rise and, as a result, NAFLD in children is becoming more pr...

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Published inClinics in liver disease Vol. 22; no. 4; p. 723
Main Authors Smith, Sara Kathryn, Perito, Emily R
Format Journal Article
LanguageEnglish
Published United States 01.11.2018
Subjects
Adolescent
Child
Child, Preschool
Disease Progression
Humans
Life Style
Mass Screening
Non-alcoholic Fatty Liver Disease - diagnosis
Non-alcoholic Fatty Liver Disease - drug therapy
Non-alcoholic Fatty Liver Disease - epidemiology
Risk Factors
NAFLD
Fatty liver disease
NASH
Pediatric
Steatohepatitis
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Abstract Pediatric nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in children. The spectrum of NAFLD ranges from steatosis to nonalcoholic steatohepatitis (NASH) to fibrosis. Obesity rates in children continue to rise and, as a result, NAFLD in children is becoming more prevalent. The pathophysiology, natural history, and progression of disease are still being elucidated but NAFLD/NASH in children may represent a more severe phenotype that will benefit from early identification and management.
AbstractList Pediatric nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in children. The spectrum of NAFLD ranges from steatosis to nonalcoholic steatohepatitis (NASH) to fibrosis. Obesity rates in children continue to rise and, as a result, NAFLD in children is becoming more prevalent. The pathophysiology, natural history, and progression of disease are still being elucidated but NAFLD/NASH in children may represent a more severe phenotype that will benefit from early identification and management.
Author Perito, Emily R
Smith, Sara Kathryn
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  organization: Department of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, 550 16th Street, 5th Floor, Mail Code 0136, San Francisco, CA 94143, USA. Electronic address: Kathryn.Smith@ucsf.edu
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  givenname: Emily R
  surname: Perito
  fullname: Perito, Emily R
  organization: Department of Pediatric Gastroenterology, Hepatology, and Nutrition, University of California, San Francisco, 550 16th Street, 5th Floor, Mail Code 0136, San Francisco, CA 94143, USA
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Keywords NAFLD
Fatty liver disease
NASH
Pediatric
Steatohepatitis
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SubjectTerms Adolescent
Child
Child, Preschool
Disease Progression
Humans
Life Style
Mass Screening
Non-alcoholic Fatty Liver Disease - diagnosis
Non-alcoholic Fatty Liver Disease - drug therapy
Non-alcoholic Fatty Liver Disease - epidemiology
Risk Factors
Title Nonalcoholic Liver Disease in Children and Adolescents
URI https://www.ncbi.nlm.nih.gov/pubmed/30266159
Volume 22
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