Metabolic phenotypes and the gut microbiota in response to dietary resistant starch type 2 in normal-weight subjects: a randomized crossover trial

• Published in: Scientific reports Vol. 9; no. 1; p. 4736
• Main Authors: Zhang, Lei, Ouyang, Yang, Li, Huating, Shen, Li, Ni, Yueqiong, Fang, Qichen, Wu, Guangyu, Qian, Lingling, Xiao, Yunfeng, Zhang, Jing, Yin, Peiyuan, Panagiotou, Gianni, Xu, Guowang, Ye, Jianping, Jia, Weiping
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 20.03.2019; Nature Publishing Group
• Subjects: 692/700/2814; 692/700/2817; Abundance; Acetic acid; Adolescent; Adult; Amylose; Amylose - metabolism; Bacteria - metabolism; Body fat; Cholesterol; Cross-Over Studies; Diet - methods; Dietary Carbohydrates - metabolism; Dietary supplements; Fat metabolism; Fatty acids; Fatty Acids, Volatile - metabolism; Feces - microbiology; Female; Gastrointestinal Hormones - metabolism; Gastrointestinal Microbiome - physiology; Glucagon; Glucagon-like peptide 1; Glucagon-Like Peptide 1 - metabolism; Glucose metabolism; Gut microbiota; Hormones; Humanities and Social Sciences; Humans; Insulin; Intestinal microflora; Low density lipoprotein; Male; Metabolism; Metabolites; Microbiota; Middle Aged; multidisciplinary; Peptides; Phenotype; Phenotypes; rRNA 16S; Science; Science (multidisciplinary); Secretion; Starch; Starch - metabolism; Urea; Young Adult

Resistant starch (RS) has been reported to reduce body fat in obese mice. However, this effect has not been demonstrated in humans. In this study, we tested the effects of RS in 19 volunteers with normal body weights. A randomized, double-blinded and crossover design clinical trial was conducted. Th...