Clinical effects and gut microbiota changes of using probiotics, prebiotics or synbiotics in inflammatory bowel disease: a systematic review and meta-analysis

• Published in: European journal of nutrition Vol. 60; no. 5; pp. 2855 - 2875
• Main Authors: Zhang, Xiao-Feng, Guan, Xiao-Xian, Tang, Yu-Jun, Sun, Jin-Feng, Wang, Xiao-Kai, Wang, Wei-Dong, Fan, Jian-Ming
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.08.2021; Springer Nature B.V
• Subjects: Bifidobacterium; Chemistry; Chemistry and Materials Science; Clinical trials; Digestive system; Dosage; Gastrointestinal tract; Gut microbiota; Inflammatory bowel disease; Inflammatory bowel diseases; Intestinal microflora; intestinal microorganisms; Intestine; intestines; Lactobacillus; Meta-analysis; Microbiota; Nutrition; Original Contribution; Patients; Prebiotics; Probiotics; Remission; Remission (Medicine); Statistical analysis; Systematic review; Ulcerative colitis; Inflammatory bowel disease; Gut microbiota; Probiotics; Remission; Synbiotics; Prebiotics

Purpose Probiotics have been reported to be beneficial for inflammatory bowel disease (IBD), but the types, number of strains, dosage, and intervention time of probiotics used remain controversial. Furthermore, the changes of gut microbiota in IBD’s patients are also intriguing. Thus, this meta-anal...