The external evocation and movement-related modulation of motor cortex inhibition in children and adolescents with Tourette syndrome – a TMS/EEG study

• Published in: Frontiers in neuroscience Vol. 17; p. 1209801
• Main Authors: Schmidgen, Julia, Konrad, Kerstin, Roessner, Veit, Bender, Stephan
• Format: Journal Article
• Language: English
• Published: Lausanne Frontiers Research Foundation 19.10.2023; Frontiers Media S.A
• Subjects: Adolescents; Attention deficit hyperactivity disorder; Child & adolescent psychiatry; Child development; Children; Comorbidity; Cortex (motor); EEG; Excitability; Gilles de la Tourette syndrome; inhibition; Intelligence tests; Investigations; Magnetic fields; MEP; N100; Neuroscience; Teenagers; TMS; Tourette syndrome; Transcranial magnetic stimulation; γ-Aminobutyric acid; γ-Aminobutyric acid B receptors

Objective: This study tested the reactivity of motor cortex inhibition to different intensities of external stimulation by transcranial magnetic stimulation (TMS) and its internal modulation during different motor states in children and adolescents with Tourette syndrome. Methods: TMS-evoked N100 se...