BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states - Beumer, Joep; Puschhof, Jens; Yengej, Fjodor Yousef; Zhao, Lianzheng; Martinez-Silgado, Adriana; Blotenburg, Marloes; Begthel, Harry; Boot, Charelle; van Oudenaarden, Alexander; Chen, Ye-Guang; Clevers, Hans (Cell reports (Cambridge), 2022)
Keywords: Animals; BMP signaling; Bone Morphogenetic Proteins - metabolism; Cell Differentiation; CRISPR-Cas9; enterocytes; Enterocytes - metabolism; Goblet Cells; intestinal differentiation; Intestinal Mucosa - metabolism; Intestine, Small - metabolism; Mice; organoids; single-cell RNA sequencing; single-cell RNA sequencing; BMP signaling; intestinal differentiation; enterocytes; organoids; CRISPR-Cas9