Evidence of Coronavirus (CoV) Pathogenesis and Emerging Pathogen SARS-CoV-2 in the Nervous System: A Review on Neurological Impairments and Manifestations

• Published in: Journal of molecular neuroscience Vol. 71; no. 11; pp. 2192 - 2209
• Main Authors: Jha, Niraj Kumar, Ojha, Shreesh, Jha, Saurabh Kumar, Dureja, Harish, Singh, Sachin Kumar, Shukla, Shakti D., Chellappan, Dinesh Kumar, Gupta, Gaurav, Bhardwaj, Shanu, Kumar, Neeraj, Jeyaraman, Madhan, Jain, Rashmi, Muthu, Sathish, Kar, Rohan, Kumar, Dhruv, Goswami, Vineet Kumar, Ruokolainen, Janne, Kesari, Kavindra Kumar, Singh, Sandeep Kumar, Dua, Kamal
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.11.2021; Springer Nature B.V
• Subjects: Abnormalities; Adolescent; Adult; Angiotensin-Converting Enzyme 2 - physiology; Asymptomatic Infections; Autoimmune Diseases of the Nervous System - etiology; Biomedical and Life Sciences; Biomedicine; Blood-Brain Barrier; Cell Biology; Central nervous system; Cerebrovascular Disorders - etiology; Child; Communicable Diseases, Emerging; Coronavirus Infections - complications; Coronaviruses; COVID-19; COVID-19 - complications; COVID-19 - immunology; COVID-19 - physiopathology; Encephalitis; Encephalomyelitis; Encephalopathy; Guillain-Barre syndrome; Hemorrhage; Humans; Hypoxia - etiology; Hypoxia - physiopathology; Infections; Ischemia; Knowledge bases (artificial intelligence); Meningitis; Muscles; Nervous system; Nervous System - virology; Nervous System Diseases - etiology; Nervous System Diseases - immunology; Nervous System Diseases - physiopathology; Neurochemistry; Neurology; Neurosciences; Olfaction; Organ Specificity; Organs; Pandemics; Pathogenesis; Peripheral nervous system; Proteomics; Receptors, Virus - physiology; Respiratory diseases; Respiratory system; SARS-CoV-2 - pathogenicity; Severe acute respiratory syndrome; Severe Acute Respiratory Syndrome - complications; Severe acute respiratory syndrome coronavirus 2; Smell; Synapses - virology; Thromboembolism; Thrombosis; Viral diseases; Viral Tropism; Viruses; Young Adult; Coronavirus (CoV); COVID-19; Neuropathogenesis; ACE2; SARS-CoV-2; Multiple sclerosis; Nervous system; Cerebrovascular disease; Guillain-Barré syndrome (GBS)

The coronavirus disease 2019 (COVID-19) pandemic is an issue of global significance that has taken the lives of many across the world. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus responsible for its pathogenesis. The pulmonary manifestations of COVID-19 have been well d...