Change in matrix metalloproteinase 2, 3, and 9 levels at the time of and after acute atherothrombotic myocardial infarction

• Published in: Journal of thrombosis and thrombolysis Vol. 49; no. 2; pp. 235 - 244
• Main Authors: Owolabi, Ugochukwu Shola, Amraotkar, Alok Ravindra, Coulter, Amanda R., Singam, Narayana Sarma V., Aladili, Bahjat N., Singh, Ayesha, Trainor, Patrick James, Mitra, Riten, DeFilippis, Andrew Paul
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2020; Springer Nature B.V
• Subjects: Adult; Aged; Atherosclerosis - blood; Atherosclerosis - diagnostic imaging; Biomarkers - blood; Cardiology; Cardiovascular disease; Cohort Studies; Coronary artery; Electrocardiography; Female; Follow-Up Studies; Gelatinase A; Gelatinase B; Health risk assessment; Heart attacks; Heart diseases; Hematology; Humans; Male; Matrix metalloproteinase; Matrix Metalloproteinase 2 - blood; Matrix Metalloproteinase 3 - blood; Matrix Metalloproteinase 9 - blood; Medicine; Medicine & Public Health; Metalloproteinase; Middle Aged; Myocardial infarction; Myocardial Infarction - blood; Myocardial Infarction - diagnostic imaging; Prospective Studies; Stromelysin 1; Thrombosis - blood; Thrombosis - diagnostic imaging; Extracellular matrix; Atherothrombosis; Acute myocardial infarction; Metalloproteinases

Elevated measures of matrix metalloproteinases (MMPs) are associated with acute myocardial infarction (MI), but it is not known how long these changes persist post-MI or if these measures differ between atherothrombotic versus non-atherothrombotic MI. MMPs-2, 3, and 9 were measured in 80 subjects wi...