Dynamics and Predictors of Cognitive Impairment along the Disease Course in Multiple Sclerosis

• Published in: Journal of personalized medicine Vol. 11; no. 11; p. 1107
• Main Authors: Lopez-Soley, Elisabet, Martinez-Heras, Eloy, Andorra, Magi, Solanes, Aleix, Radua, Joaquim, Montejo, Carmen, Alba-Arbalat, Salut, Sola-Valls, Nuria, Pulido-Valdeolivas, Irene, Sepulveda, Maria, Romero-Pinel, Lucia, Munteis, Elvira, Martínez-Rodríguez, Jose E., Blanco, Yolanda, Martinez-Lapiscina, Elena H., Villoslada, Pablo, Saiz, Albert, Solana, Elisabeth, Llufriu, Sara
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 28.10.2021; MDPI
• Subjects: Age; Cognition & reasoning; Cognitive ability; Cortex (cingulate); Cortex (temporal); Datasets; Information processing; Learning algorithms; Machine learning; Magnetic resonance imaging; Medicin och hälsovetenskap; Memory; Multiple sclerosis; Neuroimaging; Patients; Precision medicine; Semantics; Software; Variables; Volumetric analysis

(1) Background: The evolution and predictors of cognitive impairment (CI) in multiple sclerosis (MS) are poorly understood. We aimed to define the temporal dynamics of cognition throughout the disease course and identify clinical and neuroimaging measures that predict CI. (2) Methods: This paper fea...