A cross-trial comparison of single-agent ibrutinib versus chlorambucil-obinutuzumab in previously untreated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma

Saved in:
Bibliographic Details
Published inHaematologica (Roma) Vol. 105; no. 4; pp. e164 - e168
Main Authors Tedeschi, Alessandra, Greil, Richard, Demirkan, Fatih, Robak, Tadeusz, Moreno, Carol, Barr, Paul M., Anz, Bertrand, Simpson, David, Gaidano, Gianluca, Bairey, Osnat, Stevens, Don, Gill, Devinder, Flinn, Ian W., Kipps, Thomas J., Burger, Jan A., Lin, Jennifer, Webb, Thomas, Fedorov, Viktor, Styles, Lori, Gribben, John G.
Format Journal Article
LanguageEnglish
Published Italy Ferrata Storti Foundation 01.04.2020
Subjects
Adenine - analogs & derivatives
Antibodies, Monoclonal, Humanized - therapeutic use
Chlorambucil - therapeutic use
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy
Online Only
Piperidines
Online AccessGet full text

Cover

Author Barr, Paul M.
Gribben, John G.
Flinn, Ian W.
Fedorov, Viktor
Gaidano, Gianluca
Robak, Tadeusz
Anz, Bertrand
Stevens, Don
Bairey, Osnat
Webb, Thomas
Moreno, Carol
Burger, Jan A.
Greil, Richard
Tedeschi, Alessandra
Kipps, Thomas J.
Gill, Devinder
Simpson, David
Styles, Lori
Demirkan, Fatih
Lin, Jennifer
AuthorAffiliation 9 Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
17 Janssen Ltd, High Wycombe, UK
1 ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
7 Tennessee Oncology, Chattanooga, TN, USA
15 The University of Texas MD Anderson Cancer Center, Houston, TX, USA
18 Barts Cancer Institute, Queen Mary University of London, London, UK
6 Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA
2 Paracelsus Medical University Salzburg, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria
8 North Shore Hospital, Auckland, New Zealand
10 Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
4 Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
5 Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
11 Norton Cancer Institute, Louisville, KY, USA
13 Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN, USA
16 Pharmacyclics
AuthorAffiliation_xml – name: 7 Tennessee Oncology, Chattanooga, TN, USA
– name: 4 Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland
– name: 11 Norton Cancer Institute, Louisville, KY, USA
– name: 13 Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN, USA
– name: 15 The University of Texas MD Anderson Cancer Center, Houston, TX, USA
– name: 14 University of California, San Diego, Moores Cancer Center, La Jolla, CA, USA
– name: 1 ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy
– name: 18 Barts Cancer Institute, Queen Mary University of London, London, UK
– name: 2 Paracelsus Medical University Salzburg, Salzburg Cancer Research Institute, Cancer Cluster Salzburg, Salzburg, Austria
– name: 12 Princess Alexandra Hospital, Brisbane, Australia
– name: 16 Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA, USA
– name: 10 Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
– name: 5 Hospital de la Santa Creu i Sant Pau, Autonomous University of Barcelona, Barcelona, Spain
– name: 8 North Shore Hospital, Auckland, New Zealand
– name: 6 Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA
– name: 17 Janssen Ltd, High Wycombe, UK
– name: 3 Dokuz Eylul University, Izmir, Turkey
– name: 9 Amedeo Avogadro University of Eastern Piedmont, Novara, Italy
Author_xml – sequence: 1
  givenname: Alessandra
  surname: Tedeschi
  fullname: Tedeschi, Alessandra
– sequence: 2
  givenname: Richard
  surname: Greil
  fullname: Greil, Richard
– sequence: 3
  givenname: Fatih
  surname: Demirkan
  fullname: Demirkan, Fatih
– sequence: 4
  givenname: Tadeusz
  surname: Robak
  fullname: Robak, Tadeusz
– sequence: 5
  givenname: Carol
  surname: Moreno
  fullname: Moreno, Carol
– sequence: 6
  givenname: Paul M.
  surname: Barr
  fullname: Barr, Paul M.
– sequence: 7
  givenname: Bertrand
  surname: Anz
  fullname: Anz, Bertrand
– sequence: 8
  givenname: David
  surname: Simpson
  fullname: Simpson, David
– sequence: 9
  givenname: Gianluca
  surname: Gaidano
  fullname: Gaidano, Gianluca
– sequence: 10
  givenname: Osnat
  surname: Bairey
  fullname: Bairey, Osnat
– sequence: 11
  givenname: Don
  surname: Stevens
  fullname: Stevens, Don
– sequence: 12
  givenname: Devinder
  surname: Gill
  fullname: Gill, Devinder
– sequence: 13
  givenname: Ian W.
  surname: Flinn
  fullname: Flinn, Ian W.
– sequence: 14
  givenname: Thomas J.
  surname: Kipps
  fullname: Kipps, Thomas J.
– sequence: 15
  givenname: Jan A.
  surname: Burger
  fullname: Burger, Jan A.
– sequence: 16
  givenname: Jennifer
  surname: Lin
  fullname: Lin, Jennifer
– sequence: 17
  givenname: Thomas
  surname: Webb
  fullname: Webb, Thomas
– sequence: 18
  givenname: Viktor
  surname: Fedorov
  fullname: Fedorov, Viktor
– sequence: 19
  givenname: Lori
  surname: Styles
  fullname: Styles, Lori
– sequence: 20
  givenname: John G.
  surname: Gribben
  fullname: Gribben, John G.
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31413095$$D View this record in MEDLINE/PubMed
BookMark eNp9Uk1vEzEQXaEimhb-AUI-ctngz7XNAamq-KhUiQucrVmvN3HxroPtTRV-Fz-QTdJWhAMnjzzvvRnNexfV2RhHV1WvCV4yRvm7NbgBSgxLioleUsokZ8-qBRGa1kpSclYtMNO4brBU59VFzncYU6y1fFGdM8IJw1osqt9XyKaYc12Sh4BsHDaQfI4jij3KflwFV8PKjQX5Nk3Fj75FW5fylJFdh5hgaCfrQx1bP05l-jUN0CI_ok1yWx-nHHZoGktyUFyHNlD8LJXRvS_rmZ_i6C0Ku2GzjnZX9rWbfrjBA4oJ5QFCOO0e6gFeVs97CNm9engvq--fPn67_lLffv18c311W1sueallyxVXvRKk76TQoJWCRjnLeNtZiRtQPei-Yb3AvRBUNZRLxqRgohfcKcUuq5ujbhfhzmySHyDtTARvDh8xrQykebHgDG6E4LrhbdN0HHOqQBMrGqk7gFZyPmt9OGptpnZwnZ3vkCCciJ52Rr82q7g1kmAtGZkF3j4IpPhzcrmYwWfrQoDRzYc2lMp5d01oM0Pf_D3racij7TOAHwEH75PrnyAEm326zGO6zD5d5piumfb-H5r1ZfY07jf24f_kP_Hd3lo
CitedBy_id crossref_primary_10_1016_j_clinthera_2020_08_017
crossref_primary_10_1007_s00277_021_04536_6
crossref_primary_10_3389_fonc_2022_1033413
crossref_primary_10_3324_haematol_2021_279012
crossref_primary_10_1080_14712598_2022_2145881
ContentType Journal Article
Copyright Copyright© 2020 Ferrata Storti Foundation 2020
Copyright_xml – notice: Copyright© 2020 Ferrata Storti Foundation 2020
DBID AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
DOA
DOI 10.3324/haematol.2019.223743
DatabaseName CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
PubMed Central (Full Participant titles)
Directory of Open Access Journals - May need to register for free articles
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Anatomy & Physiology
EISSN 1592-8721
EndPage e168
ExternalDocumentID oai_doaj_org_article_06554964b66d40428a91c5679daab744
PMC7109731
31413095
10_3324_haematol_2019_223743
Genre Letter
Randomized Controlled Trial
GroupedDBID ---
29I
2WC
53G
5GY
5RE
5VS
AAFWJ
AAYXX
ADBBV
AENEX
AFPKN
ALMA_UNASSIGNED_HOLDINGS
AOIJS
BAWUL
BCNDV
BTFSW
C1A
CITATION
CS3
DIK
E3Z
EBS
EJD
F5P
FRP
GROUPED_DOAJ
H13
HYE
KQ8
OK1
OVT
P2P
RHI
RNS
RPM
SJN
TFS
TR2
UDS
W8F
WOQ
WOW
CGR
CUY
CVF
ECM
EIF
NPM
7X8
5PM
ID FETCH-LOGICAL-c474t-7b4848f851fd759a988a68ec34bdc706a8fa9f63f50f55286247337535f54e883
IEDL.DBID DOA
ISSN 0390-6078
1592-8721
IngestDate Wed Aug 27 01:30:07 EDT 2025
Thu Aug 21 18:16:55 EDT 2025
Fri Jul 11 02:37:36 EDT 2025
Mon Jul 21 05:56:07 EDT 2025
Tue Jul 01 04:22:14 EDT 2025
Thu Apr 24 23:11:56 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 4
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c474t-7b4848f851fd759a988a68ec34bdc706a8fa9f63f50f55286247337535f54e883
Notes SourceType-Scholarly Journals-1
ObjectType-Correspondence-1
content type line 23
ObjectType-Undefined-2
OpenAccessLink https://doaj.org/article/06554964b66d40428a91c5679daab744
PMID 31413095
PQID 2273759126
PQPubID 23479
ParticipantIDs doaj_primary_oai_doaj_org_article_06554964b66d40428a91c5679daab744
pubmedcentral_primary_oai_pubmedcentral_nih_gov_7109731
proquest_miscellaneous_2273759126
pubmed_primary_31413095
crossref_primary_10_3324_haematol_2019_223743
crossref_citationtrail_10_3324_haematol_2019_223743
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2020-04-01
PublicationDateYYYYMMDD 2020-04-01
PublicationDate_xml – month: 04
  year: 2020
  text: 2020-04-01
  day: 01
PublicationDecade 2020
PublicationPlace Italy
PublicationPlace_xml – name: Italy
PublicationTitle Haematologica (Roma)
PublicationTitleAlternate Haematologica
PublicationYear 2020
Publisher Ferrata Storti Foundation
Publisher_xml – name: Ferrata Storti Foundation
SSID ssj0020997
Score 2.3237512
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
StartPage e164
SubjectTerms Adenine - analogs & derivatives
Antibodies, Monoclonal, Humanized - therapeutic use
Chlorambucil - therapeutic use
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - drug therapy
Online Only
Piperidines
Title A cross-trial comparison of single-agent ibrutinib versus chlorambucil-obinutuzumab in previously untreated patients with chronic lymphocytic leukemia or small lymphocytic lymphoma
URI https://www.ncbi.nlm.nih.gov/pubmed/31413095
https://www.proquest.com/docview/2273759126
https://pubmed.ncbi.nlm.nih.gov/PMC7109731
https://doaj.org/article/06554964b66d40428a91c5679daab744
Volume 105
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQD4gLgpZHClRGQtxMN7Fjx8cFUVVI5USl3iLbsbUReVTd5LD8Ln4gM0521SCkXrhFechO5otmPnvmG0I-SOtMZmTOhFw5JoQLTAPHZtLK1MgK6FtM-b_6Li-vxbeb_OZeqy_MCZvkgacPdw4uEiiMFFbKSmCAb3Tqcql0ZYxVIiqBgs_bk6mZamE9aNw_0ECOwAtORXMcoofzjUEx1B63HVL9CbyjEnzhlKJ2_78Czr_zJu85ootn5OkcQdL1NPPn5JHvjsnJuoPR2h39SGNOZ1wsPyaPr-at8xPye03j4Cz26aDu0H-Q9oHigkHjmcE6KwoEGtDY1ZZiysa4pW4DpN60dnR1w7BebBzGX2NrLK07eot5wv24bXZ07GLauq_orNa6pbjMC89HAV7a7AA6vdsNeOzHn76tDe3v6LY1TbO8Go9b84JcX3z98eWSzS0bmBNKDExZUYgiQBgXKpVro4vCyMI7Lmzl1EqaIhgdJA_5KuR5htUpinOgTHnIhS8K_pIcdX3nXxMaVEjTyqY-s1qozBYaghcjAVyCW1OtEsL3NivdrGeObTWaEngNWrrcW7pES5eTpRPCDk_dTnoeD9z_GeFwuBfVuOMJwGg5Y7R8CKMJeb8HUwl_L27JmM6DaWAQBW-v00wm5NUErsNQPMUAQ-cJUQvYLeayvNLVm6gQjgm2iqen_2Pyb8iTDNcYYrbSW3I03I3-HQRigz2L_9xZXCH7A_qZNcA
linkProvider Directory of Open Access Journals
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+cross-trial+comparison+of+single-agent+ibrutinib+versus+chlorambucil-obinutuzumab+in+previously+untreated+patients+with+chronic+lymphocytic+leukemia+or+small+lymphocytic+lymphoma&rft.jtitle=Haematologica+%28Roma%29&rft.au=Tedeschi%2C+Alessandra&rft.au=Greil%2C+Richard&rft.au=Demirkan%2C+Fatih&rft.au=Robak%2C+Tadeusz&rft.date=2020-04-01&rft.eissn=1592-8721&rft.volume=105&rft.issue=4&rft.spage=e164&rft_id=info:doi/10.3324%2Fhaematol.2019.223743&rft_id=info%3Apmid%2F31413095&rft.externalDocID=31413095
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0390-6078&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0390-6078&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0390-6078&client=summon