The Longitudinal Effects of Non-injection Substance Use on Sustained HIV Viral Load Undetectability Among MSM and Heterosexual Men in Brazil and Thailand: The Role of ART Adherence and Depressive Symptoms (HPTN 063)

• Published in: AIDS and behavior Vol. 23; no. 3; pp. 649 - 660
• Main Authors: Tsuyuki, Kiyomi, Shoptaw, Steven J., Ransome, Yusuf, Chau, Gordon, Rodriguez-Diaz, Carlos E., Friedman, Ruth K., Srithanaviboonchai, Kriengkrai, Li, Sue, Mimiaga, Matthew J., Mayer, Kenneth H., Safren, Steven A.
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.03.2019; Springer Nature B.V
• Subjects: Adhesion; Adult; Alcohol; Alcohol abuse; Alcohols; Anti-HIV Agents - therapeutic use; Antiretroviral drugs; Antiretroviral therapy; Brazil - epidemiology; Cannabis; Depression - psychology; Drug use; Drug Users; Female; Health Psychology; Heterosexuality; Heterosexuality - psychology; HIV; HIV Infections - drug therapy; HIV Infections - epidemiology; HIV Infections - psychology; HIV Infections - virology; HIV-1 - drug effects; Homosexuality, Male - psychology; Human immunodeficiency virus; Humans; Infectious Diseases; Injection; Longitudinal Studies; Male; Marijuana; Medication Adherence - psychology; Medication Adherence - statistics & numerical data; Medicine; Medicine & Public Health; Men; Mens health; Mental depression; Middle Aged; Observational studies; Original Paper; Patient compliance; Public Health; Signs and symptoms; Statistical models; Stimulants; Substance abuse; Substance use; Substance-Related Disorders - complications; Substance-Related Disorders - epidemiology; Substance-Related Disorders - psychology; Symptoms; Thailand - epidemiology; Viral Load; Young Adult; Zambia - epidemiology; Brazil; Thailand; Zambia; Substance use; Adherence; Depression; HIV; Undetectable viral load

The effect of non-injection substance use on HIV viral load (VL) is understudied in international settings. Data are from HPTN063, a longitudinal observational study of HIV-infected individuals in Brazil, Thailand, and Zambia, with focus on men with VL data (Brazil = 146; Thailand = 159). Generalize...