EVLncRNAs: a manually curated database for long non-coding RNAs validated by low-throughput experiments
Abstract Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As...
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| Published in | Nucleic acids research Vol. 46; no. D1; pp. D100 - D105 |
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| Main Authors | , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Oxford University Press
04.01.2018
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Abstract
Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As more lncRNAs are validated by low-throughput experiments, several databases were established for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases or interactions). Thus, it is highly desirable to have a comprehensive dataset for experimentally validated lncRNAs as a central repository for all of their structures, functions and phenotypes. Here, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to 1 May 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species that is 2.9 times larger than the current largest database for experimentally validated lncRNAs. Seventy-four percent lncRNA entries are partially or completely new, comparing to all existing experimentally validated databases. The established database allows users to browse, search and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs. |
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| AbstractList | Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As more lncRNAs are validated by low-throughput experiments, several databases were established for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases or interactions). Thus, it is highly desirable to have a comprehensive dataset for experimentally validated lncRNAs as a central repository for all of their structures, functions and phenotypes. Here, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to 1 May 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species that is 2.9 times larger than the current largest database for experimentally validated lncRNAs. Seventy-four percent lncRNA entries are partially or completely new, comparing to all existing experimentally validated databases. The established database allows users to browse, search and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs. Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As more lncRNAs are validated by low-throughput experiments, several databases were established for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases or interactions). Thus, it is highly desirable to have a comprehensive dataset for experimentally validated lncRNAs as a central repository for all of their structures, functions and phenotypes. Here, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to 1 May 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species that is 2.9 times larger than the current largest database for experimentally validated lncRNAs. Seventy-four percent lncRNA entries are partially or completely new, comparing to all existing experimentally validated databases. The established database allows users to browse, search and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs . Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As more lncRNAs are validated by low-throughput experiments, several databases were established for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases or interactions). Thus, it is highly desirable to have a comprehensive dataset for experimentally validated lncRNAs as a central repository for all of their structures, functions and phenotypes. Here, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to 1 May 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species that is 2.9 times larger than the current largest database for experimentally validated lncRNAs. Seventy-four percent lncRNA entries are partially or completely new, comparing to all existing experimentally validated databases. The established database allows users to browse, search and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs.Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As more lncRNAs are validated by low-throughput experiments, several databases were established for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases or interactions). Thus, it is highly desirable to have a comprehensive dataset for experimentally validated lncRNAs as a central repository for all of their structures, functions and phenotypes. Here, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to 1 May 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species that is 2.9 times larger than the current largest database for experimentally validated lncRNAs. Seventy-four percent lncRNA entries are partially or completely new, comparing to all existing experimentally validated databases. The established database allows users to browse, search and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs. Abstract Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates produced by high-throughput experimental and/or computational techniques to facilitate classification, assessment and validation. As more lncRNAs are validated by low-throughput experiments, several databases were established for experimentally validated lncRNAs. However, these databases are small in scale (with a few hundreds of lncRNAs only) and specific in their focuses (plants, diseases or interactions). Thus, it is highly desirable to have a comprehensive dataset for experimentally validated lncRNAs as a central repository for all of their structures, functions and phenotypes. Here, we established EVLncRNAs by curating lncRNAs validated by low-throughput experiments (up to 1 May 2016) and integrating specific databases (lncRNAdb, LncRANDisease, Lnc2Cancer and PLNIncRBase) with additional functional and disease-specific information not covered previously. The current version of EVLncRNAs contains 1543 lncRNAs from 77 species that is 2.9 times larger than the current largest database for experimentally validated lncRNAs. Seventy-four percent lncRNA entries are partially or completely new, comparing to all existing experimentally validated databases. The established database allows users to browse, search and download as well as to submit experimentally validated lncRNAs. The database is available at http://biophy.dzu.edu.cn/EVLncRNAs. |
| Author | Wang, Jihua Zhou, Bailing Qu, Yuanxu Zhou, Yaoqi Yu, Jiafeng Dou, Xianghua Song, Feng Guo, Chengang Cao, Zanxia Hu, Guodong Zhao, Huiying Yang, Yuedong |
| AuthorAffiliation | College of Physics and Electronic Information, Dezhou University, Dezhou 253023, China Department of Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100069, China Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD 4059, Australia Institute for Glycomics and School of Information and Communication Technology, Griffith University, Gold Coast, QLD 4222, Australia |
| AuthorAffiliation_xml | – name: Department of Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100069, China – name: Institute for Glycomics and School of Information and Communication Technology, Griffith University, Gold Coast, QLD 4222, Australia – name: College of Physics and Electronic Information, Dezhou University, Dezhou 253023, China – name: Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD 4059, Australia – name: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China |
| Author_xml | – sequence: 1 givenname: Bailing orcidid: 0000-0002-9958-5699 surname: Zhou fullname: Zhou, Bailing email: yaoqi.zhou@griffith.edu.au organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 2 givenname: Huiying surname: Zhao fullname: Zhao, Huiying organization: Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD 4059, Australia – sequence: 3 givenname: Jiafeng surname: Yu fullname: Yu, Jiafeng organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 4 givenname: Chengang surname: Guo fullname: Guo, Chengang organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 5 givenname: Xianghua surname: Dou fullname: Dou, Xianghua organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 6 givenname: Feng surname: Song fullname: Song, Feng organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 7 givenname: Guodong surname: Hu fullname: Hu, Guodong organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 8 givenname: Zanxia surname: Cao fullname: Cao, Zanxia organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 9 givenname: Yuanxu surname: Qu fullname: Qu, Yuanxu organization: Department of Surgery, Beijing Tiantan Hospital, Capital Medical University, Beijing 100069, China – sequence: 10 givenname: Yuedong orcidid: 0000-0002-6782-2813 surname: Yang fullname: Yang, Yuedong organization: Institute for Glycomics and School of Information and Communication Technology, Griffith University, Gold Coast, QLD 4222, Australia – sequence: 11 givenname: Yaoqi orcidid: 0000-0002-9958-5699 surname: Zhou fullname: Zhou, Yaoqi email: yaoqi.zhou@griffith.edu.au organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China – sequence: 12 givenname: Jihua surname: Wang fullname: Wang, Jihua email: yaoqi.zhou@griffith.edu.au organization: Shandong Provincial Key Laboratory of Biophysics, Institute of Biophysics, Dezhou University, Dezhou 253023, China |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/28985416$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1093/database/baw057 10.1016/0092-8674(92)90519-I 10.1186/s13059-016-0881-8 10.1186/1476-4598-10-38 10.1038/nature21374 10.1007/s00432-012-1324-x 10.1586/erm.12.134 10.1093/nar/gku1162 10.1016/j.molcel.2013.01.010 10.1093/nar/gkw1033 10.1016/j.jgg.2017.01.004 10.1038/nrm2347 10.1093/bib/bbv114 10.1093/nar/gkv1252 10.1093/nar/gku1060 10.1093/nar/gku988 10.1038/cddiscovery.2016.104 10.1002/hep.24563 10.1261/rna.044040.113 10.1093/nar/gkv1094 10.1038/ncomms14421 10.1038/nrg2521 10.1016/j.cell.2009.02.006 10.1128/MCB.10.1.28 10.1093/bioinformatics/btv148 10.1038/nature11247 10.1016/j.celrep.2012.06.003 10.1093/nar/gkm391 10.1093/nar/gkw1071 10.1093/nar/gkr823 10.1038/nature11233 10.1093/nar/gkw798 10.1016/j.cell.2009.01.035 10.1016/j.gene.2015.07.069 10.1038/ncomms6383 10.1038/cr.2014.35 10.1093/nar/gkw1104 |
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| References | ( key 20180103190601_B14) 2017; 18 ( key 20180103190601_B5) 2009; 136 ( key 20180103190601_B7) 1992; 71 ( key 20180103190601_B2) 2012; 489 ( key 20180103190601_B12) 2013; 13 ( key 20180103190601_B34) 2017; 45 ( key 20180103190601_B16) 2014; 20 ( key 20180103190601_B6) 1990; 10 ( key 20180103190601_B13) 2017; 8 ( key 20180103190601_B37) 2017; 45 ( key 20180103190601_B33) 2016; 17 ( key 20180103190601_B21) 2016; 2016 ( key 20180103190601_B10) 2017; 3 ( key 20180103190601_B32) 2014; 5 ( key 20180103190601_B31) 2013; 139 ( key 20180103190601_B11) 2011; 10 ( key 20180103190601_B1) 2012; 489 ( key 20180103190601_B27) 2013; 49 ( key 20180103190601_B17) 2015; 43 ( key 20180103190601_B23) 2013; 41 ( key 20180103190601_B8) 2009; 10 ( key 20180103190601_B4) 2008; 9 ( key 20180103190601_B26) 2015; 573 ( key 20180103190601_B3) 2009; 136 ( key 20180103190601_B38) 2007; 35 ( key 20180103190601_B18) 2015; 43 ( key 20180103190601_B24) 2016; 44 ( key 20180103190601_B30) 2014; 24 ( key 20180103190601_B29) 2012; 2 ( key 20180103190601_B9) 2017; 543 ( key 20180103190601_B22) 2015; 43 NCBI Resource Coordinators ( key 20180103190601_B35) 2017; 45 ( key 20180103190601_B15) 2015; 31 ( key 20180103190601_B25); 44 ( key 20180103190601_B19) 2012; 40 ( key 20180103190601_B28) 2011; 54 ( key 20180103190601_B20) 2016; 44 ( key 20180103190601_B36) 2017; 45 |
| References_xml | – volume: 2016 start-page: baw057 year: 2016 ident: key 20180103190601_B21 article-title: NPInter v3.0: an upgraded database of noncoding RNA-associated interactions publication-title: Database doi: 10.1093/database/baw057 – volume: 71 start-page: 515 year: 1992 ident: key 20180103190601_B7 article-title: The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus publication-title: Cell doi: 10.1016/0092-8674(92)90519-I – volume: 17 start-page: 13 year: 2016 ident: key 20180103190601_B33 article-title: A survey of best practices for RNA-seq data analysis publication-title: Genome Biol. doi: 10.1186/s13059-016-0881-8 – volume: 10 start-page: 38 year: 2011 ident: key 20180103190601_B11 article-title: The functional role of long non-coding RNA in human carcinomas publication-title: Mol. Cancer doi: 10.1186/1476-4598-10-38 – volume: 41 start-page: D983 year: 2013 ident: key 20180103190601_B23 article-title: LncRNADisease: a database for long-non-coding RNA-associated diseases publication-title: Nucleic Acids Res. – volume: 543 start-page: 199 year: 2017 ident: key 20180103190601_B9 article-title: An atlas of human long non-coding RNAs with accurate 5′ ends publication-title: Nature doi: 10.1038/nature21374 – volume: 139 start-page: 437 year: 2013 ident: key 20180103190601_B31 article-title: Long noncoding RNA CCAT1, which could be activated by c-Myc, promotes the progression of gastric carcinoma publication-title: J. Cancer Res. Clin. Oncol. doi: 10.1007/s00432-012-1324-x – volume: 13 start-page: 183 year: 2013 ident: key 20180103190601_B12 article-title: miRNAs and long noncoding RNAs as biomarkers in human diseases publication-title: Exp. Rev. Mol. Diagn. doi: 10.1586/erm.12.134 – volume: 43 start-page: D982 year: 2015 ident: key 20180103190601_B18 article-title: PNRD: a plant non-coding RNA database publication-title: Nucleic Acids Res. doi: 10.1093/nar/gku1162 – volume: 49 start-page: 1083 year: 2013 ident: key 20180103190601_B27 article-title: Repression of the long noncoding RNA-LET by histone deacetylase 3 contributes to hypoxia-mediated metastasis publication-title: Mol. Cell doi: 10.1016/j.molcel.2013.01.010 – volume: 45 start-page: D619 year: 2017 ident: key 20180103190601_B34 article-title: Genenames.org: the HGNC and VGNC resources in 2017 publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkw1033 – volume: 44 start-page: 265 ident: key 20180103190601_B25 article-title: lncRInter: a database of experimentally validated long non-coding RNA interaction publication-title: J. Genet. Genomics doi: 10.1016/j.jgg.2017.01.004 – volume: 9 start-page: 219 year: 2008 ident: key 20180103190601_B4 article-title: Small non-coding RNAs in animal development publication-title: Nat. Rev. Mol. Cell Biol. doi: 10.1038/nrm2347 – volume: 18 start-page: 9 year: 2017 ident: key 20180103190601_B14 article-title: Computational recognition for long non-coding RNA (lncRNA): software and databases publication-title: Brief. Bioinform. doi: 10.1093/bib/bbv114 – volume: 44 start-page: D203 year: 2016 ident: key 20180103190601_B20 article-title: NONCODE 2016: an informative and valuable data source of long non-coding RNAs publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkv1252 – volume: 43 start-page: D174 year: 2015 ident: key 20180103190601_B17 article-title: An update on LNCipedia: a database for annotated human lncRNA sequences publication-title: Nucleic Acids Res. doi: 10.1093/nar/gku1060 – volume: 43 start-page: D168 year: 2015 ident: key 20180103190601_B22 article-title: lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs publication-title: Nucleic Acids Res. doi: 10.1093/nar/gku988 – volume: 3 start-page: 16104 year: 2017 ident: key 20180103190601_B10 article-title: Long noncoding RNA: noncoding and not coded publication-title: Cell Death Discov. doi: 10.1038/cddiscovery.2016.104 – volume: 54 start-page: 1679 year: 2011 ident: key 20180103190601_B28 article-title: Long noncoding RNA high expression in hepatocellular carcinoma facilitates tumor growth through enhancer of zeste homolog 2 in humans publication-title: Hepatology doi: 10.1002/hep.24563 – volume: 20 start-page: 1655 year: 2014 ident: key 20180103190601_B16 article-title: Databases for lncRNAs: a comparative evaluation of emerging tools publication-title: RNA doi: 10.1261/rna.044040.113 – volume: 44 start-page: D980 year: 2016 ident: key 20180103190601_B24 article-title: Lnc2Cancer: a manually curated database of experimentally supported lncRNAs associated with various human cancers publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkv1094 – volume: 8 start-page: 14421 year: 2017 ident: key 20180103190601_B13 article-title: Recurrently deregulated lncRNAs in hepatocellular carcinoma publication-title: Nat. Commun. doi: 10.1038/ncomms14421 – volume: 10 start-page: 155 year: 2009 ident: key 20180103190601_B8 article-title: Long non-coding RNAs: insights into functions publication-title: Nat. Rev. Genet. doi: 10.1038/nrg2521 – volume: 136 start-page: 629 year: 2009 ident: key 20180103190601_B3 article-title: Evolution and functions of long noncoding RNAs publication-title: Cell doi: 10.1016/j.cell.2009.02.006 – volume: 10 start-page: 28 year: 1990 ident: key 20180103190601_B6 article-title: The product of the H19 gene may function as an RNA publication-title: Mol. Cell. Biol. doi: 10.1128/MCB.10.1.28 – volume: 31 start-page: 2241 year: 2015 ident: key 20180103190601_B15 article-title: Computational approaches towards understanding human long non-coding RNA biology publication-title: Bioinformatics doi: 10.1093/bioinformatics/btv148 – volume: 489 start-page: 57 year: 2012 ident: key 20180103190601_B2 article-title: An integrated encyclopedia of DNA elements in the human genome publication-title: Nature doi: 10.1038/nature11247 – volume: 2 start-page: 111 year: 2012 ident: key 20180103190601_B29 article-title: The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult publication-title: Cell Rep. doi: 10.1016/j.celrep.2012.06.003 – volume: 35 start-page: W345 year: 2007 ident: key 20180103190601_B38 article-title: CPC: assess the protein-coding potential of transcripts using sequence features and support vector machine publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkm391 – volume: 45 start-page: D12 year: 2017 ident: key 20180103190601_B35 article-title: Database resources of the national center for biotechnology information publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkw1071 – volume: 40 start-page: D1187 year: 2012 ident: key 20180103190601_B19 article-title: PlantNATsDB: a comprehensive database of plant natural antisense transcripts publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkr823 – volume: 489 start-page: 101 year: 2012 ident: key 20180103190601_B1 article-title: Landscape of transcription in human cells publication-title: Nature doi: 10.1038/nature11233 – volume: 45 start-page: e2 year: 2017 ident: key 20180103190601_B37 article-title: COME: a robust coding potential calculation tool for lncRNA identification and characterization based on multiple features publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkw798 – volume: 136 start-page: 642 year: 2009 ident: key 20180103190601_B5 article-title: Origins and mechanisms of miRNAs and siRNAs publication-title: Cell doi: 10.1016/j.cell.2009.01.035 – volume: 573 start-page: 328 year: 2015 ident: key 20180103190601_B26 article-title: PLNlncRbase: a resource for experimentally identified lncRNAs in plants publication-title: Gene doi: 10.1016/j.gene.2015.07.069 – volume: 5 start-page: 5383 year: 2014 ident: key 20180103190601_B32 article-title: The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer publication-title: Nat. Commun. doi: 10.1038/ncomms6383 – volume: 24 start-page: 513 year: 2014 ident: key 20180103190601_B30 article-title: Human colorectal cancer-specific CCAT1-L lncRNA regulates long-range chromatin interactions at the MYC locus publication-title: Cell Res. doi: 10.1038/cr.2014.35 – volume: 45 start-page: D635 year: 2017 ident: key 20180103190601_B36 article-title: Ensembl 2017 publication-title: Nucleic Acids Res. doi: 10.1093/nar/gkw1104 |
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Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA... Long non-coding RNAs (lncRNAs) play important functional roles in various biological processes. Early databases were utilized to deposit all lncRNA candidates... |
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| Title | EVLncRNAs: a manually curated database for long non-coding RNAs validated by low-throughput experiments |
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