Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates - Aoyama, Michihiko; Tada, Minoru; Yokoo, Hidetomo; Demizu, Yosuke; Ishii-Watabe, Akiko (Pharmaceutical research, 2022)
Keywords: Antibodies; Antibodies, Monoclonal - pharmacology; Antineoplastic Agents, Immunological - pharmacology; Biochemistry; Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Blocking antibodies; Cell activation; Cell Line; Cell Line, Tumor; Cytotoxicity; Humans; Hydrophobicity; Immunoconjugates - pharmacology; Internalization; Medical Law; Monoclonal antibodies; Pharmacology/Toxicology; Pharmacy; Receptors, IgG; Research Paper; Tumors; aggregation; off-target toxicity; Fcγ receptors; Antibody-drug conjugates