Association of rheumatoid arthritis-related autoantibodies with pulmonary function test abnormalities in a rheumatoid arthritis registry

• Published in: Clinical rheumatology Vol. 38; no. 12; pp. 3401 - 3412
• Main Authors: Huang, Sicong, He, Xintong, Doyle, Tracy J., Zaccardelli, Alessandra, Marshall, Allison A., Friedlander, H. Maura, Blaustein, Rachel B., Smith, Elisabeth A., Cui, Jing, Iannaccone, Christine K., Mahmoud, Taysir G., Weinblatt, Michael E., Dellaripa, Paul F., Shadick, Nancy A., Sparks, Jeffrey A.
• Format: Journal Article
• Language: English
• Published: London Springer London 01.12.2019; Springer Nature B.V
• Subjects: Adult; Aged; Anti-Citrullinated Protein Antibodies - blood; Arthritis, Rheumatoid - complications; Arthritis, Rheumatoid - immunology; Autoantibodies; Citrulline; Diffusion; Female; Health risk assessment; Humans; Lung Diseases - immunology; Male; Medicine; Medicine & Public Health; Middle Aged; Morbidity; Original Article; Peptides; Peptides, Cyclic; Phenotypes; Registries; Respiratory function; Respiratory Function Tests; Rheumatoid arthritis; Rheumatoid factor; Rheumatoid Factor - blood; Rheumatology; Smoking; CCP; Pulmonary disease; RF; Rheumatoid arthritis; Serostatus

Introduction We investigated whether rheumatoid arthritis (RA)-related autoantibodies were associated with abnormalities on pulmonary function tests (PFTs). Methods We studied RA serostatus and PFT abnormalities within a RA registry. RA serostatus was assessed by research assays for cyclic citrullin...