Assessment of cerebral autoregulation using continuous-wave near-infrared spectroscopy during squat-stand maneuvers in subjects with symptoms of orthostatic intolerance

• Published in: Scientific reports Vol. 8; no. 1; pp. 13257 - 11
• Main Authors: Kim, Jae-Myoung, Choi, Jong-Kwan, Choi, Mingyu, Ji, Minsu, Hwang, Gunpil, Ko, Sang-Bae, Bae, Hyeon-Min
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 05.09.2018; Nature Publishing Group
• Subjects: 631/443/1338/2729; 692/53/2422; 692/700/1421/65; 9/10; Blood; Blood flow; Blood pressure; Cerebral blood flow; Heart rate; Hemoglobin; Humanities and Social Sciences; I.R. radiation; Infrared spectroscopy; Intolerance; multidisciplinary; Performance assessment; Prefrontal cortex; Science; Science (multidisciplinary); Spectrum analysis; Syncope; Temporal lobe; Young adults

Orthostatic lightheadedness in healthy young adults often leads to syncope in severe cases. One suggested underlying mechanism of orthostatic lightheadedness is a drop in transient blood pressure (BP); however, a decrease in BP does not always lead to a drop in cerebral blood flow (CBF) due to cereb...