Characterization of a SARS-CoV-2 EG.5.1 clinical isolate in vitro and in vivo

• Published in: Cell reports (Cambridge) Vol. 42; no. 12; p. 113580
• Main Authors: Uraki, Ryuta, Kiso, Maki, Iwatsuki-Horimoto, Kiyoko, Yamayoshi, Seiya, Ito, Mutsumi, Chiba, Shiho, Sakai-Tagawa, Yuko, Imai, Masaki, Kashima, Yukie, Koga, Michiko, Fuwa, Noriko, Okumura, Nobumasa, Hojo, Masayuki, Iwamoto, Noriko, Kato, Hideaki, Nakajima, Hideaki, Ohmagari, Norio, Yotsuyanagi, Hiroshi, Suzuki, Yutaka, Kawaoka, Yoshihiro
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 26.12.2023; Elsevier
• Subjects: antigenicity; CP: Immunology; CP: Microbiology; EG.5.1; hamster model; pathogenicity; SARS-CoV-2; transmissibility; EG.5.1; CP: Immunology; pathogenicity; antigenicity; SARS-CoV-2; transmissibility; CP: Microbiology; hamster model

EG.5.1 is a subvariant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB variant that is rapidly increasing in prevalence worldwide. However, the pathogenicity, transmissibility, and immune evasion properties of isolates of EG.5.1 are largely unknown. Here, we show that...