Major histocompatibility complex (MHC) associations with diseases in ethnic groups of the Arabian Peninsula

• Published in: Immunogenetics (New York) Vol. 73; no. 2; pp. 131 - 152
• Main Authors: Al Naqbi, Halima, Mawart, Aurélie, Alshamsi, Jawaher, Al Safar, Habiba, Tay, Guan K.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.04.2021; Springer Nature B.V
• Subjects: Allergology; Antigens; Arthritis; Autoimmune diseases; Biomedical and Life Sciences; Biomedicine; Cell Biology; Chronic conditions; Diabetes mellitus; Diabetes mellitus (insulin dependent); Gene families; Gene Function; Haplotypes; Histocompatibility antigen HLA; Human Genetics; Immunology; Insulin; Leukocytes; Major histocompatibility complex; Minority & ethnic groups; Multiple sclerosis; Myasthenia gravis; Neuromuscular junctions; Populations; Psoriasis; Psoriasis vulgaris; Public domain; Review; Rheumatoid arthritis; Skin diseases; Systemic lupus erythematosus; Arabian Peninsula; MHC; Disease association; HLA; Arab

Since the discovery of human leukocyte antigens (HLAs), the function of major histocompatibility complex (MHC) gene families in a wide range of diseases have been the subject of research for decades. In particular, the associations of autoimmune disorders to allelic variants and candidate genes enco...