Antibiotic Bacillomycin D Affects Iron Acquisition and Biofilm Formation in Bacillus velezensis through a Btr-Mediated FeuABC-Dependent Pathway

• Published in: Cell reports (Cambridge) Vol. 29; no. 5; pp. 1192 - 1202.e5
• Main Authors: Xu, Zhihui, Mandic-Mulec, Ines, Zhang, Huihui, Liu, Yan, Sun, Xinli, Feng, Haichao, Xun, Weibing, Zhang, Nan, Shen, Qirong, Zhang, Ruifu
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 29.10.2019; Elsevier
• Subjects: bacillomycin D; Bacillus; biofilm; FeuABC; interspecific competition; iron uptake; transcription factor Btr; interspecific competition; FeuABC; Bacillus; iron uptake; biofilm; bacillomycin D; transcription factor Btr

Bacillus spp. produce a wide range of secondary metabolites, including antibiotics, which have been well studied for their antibacterial properties but less so as signaling molecules. Previous results indicated that the lipopeptide bacillomycin D is a signal that promotes biofilm development of Baci...