The clinical impact of the molecular landscape of acute myeloid leukemia

• Published in: Haematologica (Roma) Vol. 108; no. 2; pp. 308 - 320
• Main Authors: Kayser, Sabine, Levis, Mark J.
• Format: Journal Article
• Language: English
• Published: Italy Fondazione Ferrata Storti 01.02.2023; Ferrata Storti Foundation
• Subjects: Gemtuzumab; Humans; Leukemia, Myeloid, Acute - diagnosis; Leukemia, Myeloid, Acute - drug therapy; Leukemia, Myeloid, Acute - genetics; Review

Research into the underlying pathogenic mechanisms of acute myeloid leukemia (AML) has led to remarkable advances in our understanding of the disease. Mutations now allow us to explore the enormous diversity among cytogenetically defined subsets of AML, particularly the large subset of cytogenetical...