Ectopic calcification and formation of mineralo-organic particles in arteries of diabetic subjects

• Published in: Scientific reports Vol. 10; no. 1; p. 8545
• Main Authors: Wu, Cheng-Yeu, Martel, Jan, Young, John D.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 22.05.2020; Nature Publishing Group
• Subjects: 631/45/612/1221; 692/53/2423; Apolipoproteins; Arteries; Arteriosclerosis; Calcification; Calcification (ectopic); Calcium phosphates; Diabetes; Diabetes mellitus (non-insulin dependent); Electron microscopy; Histology; Humanities and Social Sciences; Hyperplasia; Kidney diseases; multidisciplinary; Science; Science (multidisciplinary); Spectroscopy

Vascular calcification occurs in various diseases including atherosclerosis, chronic kidney disease and type 2 diabetes but the mechanism underlying mineral deposition remains incompletely understood. Here we examined lower limb arteries of type 2 diabetes subjects for the presence of ectopic calcif...