Depression and Accelerated Aging: The Eveningness Chronotype and Low Adherence to the Mediterranean Diet Are Associated with Depressive Symptoms in Older Subjects

• Published in: Nutrients Vol. 17; no. 1; p. 104
• Main Authors: Sorlí, José V., de la Cámara, Edurne, Fernández-Carrión, Rebeca, Asensio, Eva M., Portolés, Olga, Ortega-Azorín, Carolina, Pérez-Fidalgo, Alejandro, Villamil, Laura V., Fitó, Montserrat, Barragán, Rocío, Coltell, Oscar, Corella, Dolores
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.01.2025; MDPI
• Subjects: Aged; Aging; Aging, Premature - psychology; Analysis; Biomarkers - blood; Cardiovascular diseases; Chronic diseases; Chronic illnesses; Chronotype; Circadian Rhythm - physiology; Depression - epidemiology; Depression, Mental; Diet, Mediterranean - psychology; DNA Methylation; Epigenetic inheritance; Female; Humans; Male; Medical research; Medicine, Experimental; Mental depression; Metabolic Syndrome - psychology; Methylation; Middle Aged; Obesity; Patient Compliance; Sex Factors; Surveys and Questionnaires; Type 2 diabetes; United States; Washington, D.C; Spain; nutrition; chronic diseases; mental health; chronotype; mediterranean diet; aging; depression; methylation clocks

Background and objectives: Depression often results in premature aging, which increases the risk of other chronic diseases, but very few studies have analyzed the association between epigenetic biomarkers of aging and depressive symptoms. Similarly, limited research has examined the joint effects of...