The Ever-Increasing Array of Novel Inborn Errors of Immunity: an Interim Update by the IUIS Committee

• Published in: Journal of clinical immunology Vol. 41; no. 3; pp. 666 - 679
• Main Authors: Tangye, Stuart G., Al-Herz, Waleed, Bousfiha, Aziz, Cunningham-Rundles, Charlotte, Franco, Jose Luis, Holland, Steven M, Klein, Christoph, Morio, Tomohiro, Oksenhendler, Eric, Picard, Capucine, Puel, Anne, Puck, Jennifer, Seppänen, Mikko R. J., Somech, Raz, Su, Helen C, Sullivan, Kathleen E., Torgerson, Troy R., Meyts, Isabelle
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.04.2021; Springer Nature B.V
• Subjects: Alleles; Biomedical and Life Sciences; Biomedicine; COVID-19 - complications; COVID-19 - epidemiology; COVID-19 - virology; Diagnosis, Differential; Disease Management; Genetic Association Studies - methods; Genetic diversity; Genetic Predisposition to Disease; Genotype; Humans; Immunity; Immunity - genetics; Immunology; Infectious Diseases; Inheritance Patterns; Internal Medicine; Medical Microbiology; Original; Original Article; Phenotype; Primary immunodeficiencies; Primary Immunodeficiency Diseases - diagnosis; Primary Immunodeficiency Diseases - epidemiology; Primary Immunodeficiency Diseases - genetics; Public Health Surveillance; Risk Factors; autoinflammatory disorders; primary immunodeficiencies; Inborn errors of immunity; immune dysregulation

The most recent updated classification of inborn errors of immunity/primary immunodeficiencies, compiled by the International Union of Immunological Societies Expert Committee, was published in January 2020. Within days of completing this report, it was already out of date, evidenced by the frequent...