Construction of 3D-rendering imaging of an ischemic rat brain model using the planar FMMD technique

• Published in: Scientific reports Vol. 9; no. 1; pp. 19050 - 9
• Main Authors: Kim, Chang-Beom, Park, Sang-Jin, Jeong, Jae-Chan, Choi, Seung-Min, Krause, Hans-Joachim, Song, Dae-Yong, Hong, Hyobong
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 13.12.2019; Nature Publishing Group
• Subjects: 59; 639/166/985; 639/766/930/2735; 9/10; Animals; Brain; Brain Ischemia - diagnostic imaging; Disease Models, Animal; Humanities and Social Sciences; Imaging, Three-Dimensional; Infarction, Middle Cerebral Artery - complications; Ischemia; Magnetic Resonance Imaging; Male; Medical imaging; multidisciplinary; Neuroimaging; NMR; Nuclear magnetic resonance; Rats, Sprague-Dawley; Reactive oxygen species; Science; Science (multidisciplinary); Signal Processing, Computer-Assisted

Occlusion of the major cerebral artery usually results in brain hypoxic-ischemic injury, which evokes neuroinflammation and microglial activation. Activated microglia are considered a source of multiple neurotoxic factors, such as reactive oxygen species (ROS), in the central nervous system (CNS). W...