Involvement of cecropin B in the formation of the Aedes aegypti mosquito cuticle

• Published in: Scientific reports Vol. 7; no. 1; pp. 16395 - 17
• Main Authors: Liu, Wei-Ting, Tu, Wu-Chun, Lin, Chao-Hsiung, Yang, Ueng-Cheng, Chen, Cheng-Chen
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 27.11.2017; Nature Publishing Group
• Subjects: 13/89; 14/1; 631/136/1660/1646; 631/250/2499; 631/337/505; 631/45/535/1258; 631/601/1466; Adults; Aedes aegypti; Aquatic insects; Cecropin; Chitin; Cytoplasm; Deoxyribonucleic acid; DNA; Double-stranded RNA; Gene expression; Humanities and Social Sciences; Lamellae; Microfibrils; Mortality; Mosquitoes; multidisciplinary; Nuclei; Peptides; Prophenoloxidase; Pupae; Science; Science (multidisciplinary); Transcription

In this study, we found a mosquito antimicrobial peptide (AMP), Aedes aegypti cecropin B (Aacec B), was expressed constitutively in pupae. Knockdown in the pupae of Aacec B using double-stranded RNA (dsRNA) resulted in high mortality, the emergence of deformed adults and an impairment of pharate adu...