Neoadjuvant chemotherapy induces breast cancer metastasis through a TMEM-mediated mechanism - Karagiannis, George S; Pastoriza, Jessica M; Wang, Yarong; Harney, Allison S; Entenberg, David; Pignatelli, Jeanine; Sharma, Ved P; Xue, Emily A; Cheng, Esther; D'Alfonso, Timothy M; Jones, Joan G; Anampa, Jesus; et al. (Science translational medicine, 2017)
Keywords: Animals; Antineoplastic Combined Chemotherapy Protocols - pharmacology; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Breast Neoplasms - drug therapy; Breast Neoplasms - metabolism; Breast Neoplasms - pathology; Capillary Permeability - drug effects; Cell Proliferation - drug effects; Cyclophosphamide - pharmacology; Cyclophosphamide - therapeutic use; Doxorubicin - pharmacology; Doxorubicin - therapeutic use; Female; Humans; Macrophages - drug effects; Macrophages - pathology; Mice; Microfilament Proteins - metabolism; Neoadjuvant Therapy; Neoplasm Invasiveness; Neoplasm Metastasis; Paclitaxel - pharmacology; Paclitaxel - therapeutic use; Protein Isoforms - metabolism; Receptor, TIE-2 - metabolism; Tumor Microenvironment - drug effects; Vascular Endothelial Growth Factor A - metabolism