Efficient functional screening of a cellular cDNA library to identify severe fever with thrombocytopenia syndrome virus entry factors

• Published in: Scientific reports Vol. 10; no. 1; p. 5996
• Main Authors: Shimojima, Masayuki, Sugimoto, Satoko, Taniguchi, Satoshi, Yoshikawa, Tomoki, Kurosu, Takeshi, Saijo, Masayuki
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 07.04.2020; Nature Publishing Group
• Subjects: 13/1; 13/106; 14/35; 38/77; 42/40; 631/326/596/2557; 631/326/88; Animals; Calcium; Cell Adhesion Molecules - genetics; Chlorocebus aethiops; Dendritic cells; Fever; Gene Library; Genetic Variation; Humanities and Social Sciences; Humans; Infectious diseases; Lectins, C-Type - genetics; Liver - metabolism; Liver - virology; multidisciplinary; Phlebotomus Fever - genetics; Phlebotomus Fever - virology; Phlebovirus - physiology; Receptors, Cell Surface - genetics; Science; Science (multidisciplinary); Thrombocytopenia; Vero Cells; Virus Internalization; Virus-like particles; Viruses

The identification of host cell factors for virus entry is useful for the molecular explanation of viral tropisms and often leads to a more profound understanding of virus-induced diseases. Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus. No...