Phosphorylated chitosan accelerates dermal wound healing in diabetic wistar rats

• Published in: Glycoconjugate journal Vol. 40; no. 1; pp. 19 - 31
• Main Authors: Anushree, U., Punj, Pratik, Vasumathi, Bharati, Sanjay
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.02.2023; Springer Nature B.V
• Subjects: Angiogenesis; Animal models; Animals; Antioxidants; Antioxidants - pharmacology; Biochemistry; Biomedical and Life Sciences; Chitosan; Chitosan - chemistry; Chitosan - pharmacology; Collagen; Diabetes; Diabetes mellitus; Diabetes Mellitus, Experimental - drug therapy; Fibroblasts; Hydroxylamine; Life Sciences; Lipid peroxidation; NMR; Nuclear magnetic resonance; Original; Original Article; Pathology; Phosphorylation; Rats; Rats, Wistar; Spectroscopy, Fourier Transform Infrared; Superoxide dismutase; Wound Healing; Granulation tissue; Phosphorylation; Excisional wound; Chitosan; Diabetes mellitus

Phosphorylated chitosan (PC), a water-soluble derivative of chitosan possesses several biological and chemical properties suitable for diabetic wound healing. In the present study, we report the synthesis and diabetic wound healing capabilities of PC. Elemental analysis, FT-IR, 13 C-NMR and 31 P-NMR...