Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury - Guttenplan, Kevin A.; Stafford, Benjamin K.; El-Danaf, Rana N.; Adler, Drew I.; Münch, Alexandra E.; Weigel, Maya K.; Huberman, Andrew D.; Liddelow, Shane A. (Cell reports (Cambridge), 2020)
Keywords: Animals; astrocytes; Astrocytes - pathology; astrogliosis; Axons - drug effects; Axons - pathology; Cell Death - drug effects; Cell Shape - drug effects; Complement C1q - metabolism; Dendrites - drug effects; Dendrites - metabolism; Disease Models, Animal; glaucoma; Glaucoma - complications; Glaucoma - pathology; Glaucoma - physiopathology; glia; Gliosis - complications; Gliosis - pathology; Gliosis - physiopathology; Interleukin-1 - metabolism; Intraocular Pressure; Mice, Knockout; Microspheres; neurodegeneration; Neurons - drug effects; Neurons - pathology; neuroprotection; Neurotoxins - toxicity; optic nerve crush; reactive astrocyte; Retina - drug effects; Retina - injuries; Retina - pathology; Retinal Ganglion Cells - drug effects; Retinal Ganglion Cells - pathology; Tumor Necrosis Factor-alpha - metabolism; reactive astrocyte; glaucoma; neuroprotection; neurodegeneration; optic nerve crush; astrocytes; astrogliosis; glia