fNIRS can robustly measure brain activity during memory encoding and retrieval in healthy subjects

• Published in: Scientific reports Vol. 7; no. 1; pp. 9533 - 14
• Main Authors: Jahani, Sahar, Fantana, Antoniu L., Harper, David, Ellison, James M., Boas, David A., Forester, Brent P., Yücel, Meryem A.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 25.08.2017; Nature Publishing Group
• Subjects: 692/308; 692/53; Adult; Alzheimer's disease; Associative learning; Biomarkers; Brain - physiology; Brain Mapping - methods; Cerebral Cortex - physiology; Cortex (frontal); Cortex (parietal); Face; Female; Healthy Volunteers; Humanities and Social Sciences; Humans; Image Processing, Computer-Assisted; Infrared spectroscopy; Male; Memory; Mental Recall; multidisciplinary; Neurodegenerative diseases; Prefrontal cortex; Science; Science (multidisciplinary); Spectrum Analysis - methods; Temporal lobe; Young Adult

Early intervention in Alzheimer’s Disease (AD) requires novel biomarkers that can capture changes in brain activity at an early stage. Current AD biomarkers are expensive and/or invasive and therefore unsuitable for use as screening tools, but a non-invasive, inexpensive, easily accessible screening...