Sex-dependent dynamics of metabolism in primary mouse hepatocytes - Hochmuth, Luise; Körner, Christiane; Ott, Fritzi; Volke, Daniela; Cokan, Kaja Blagotinšek; Juvan, Peter; Brosch, Mario; Hofmann, Ute; Hoffmann, Ralf; Rozman, Damjana; Berg, Thomas; Matz-Soja, Madlen (Archives of toxicology, 2021)
Keywords: Amino acids; Animals; Aryl Hydrocarbon Hydroxylases - genetics; Biomedical and Life Sciences; Biomedicine; Clinical trials; Cytochrome P-450 Enzyme System - genetics; Cytochrome P450 Family 2 - genetics; Degradation; Drug metabolism; Drugs; Environmental Health; Fatty liver; Female; Gene expression; Gene Expression Regulation - physiology; Health services; Hepatocellular carcinoma; Hepatocytes; Hepatocytes - metabolism; Lipid metabolism; Lipids; Liver; Liver cancer; Liver diseases; Male; Males; Melatonin; Melatonin - metabolism; Metabolic pathways; Metabolism; Metabolome - physiology; Mice; Mice, Inbred C57BL; Occupational Medicine/Industrial Medicine; Organs; Oxidation; Pharmacodynamics; Pharmacology; Pharmacology/Toxicology; Proteome - physiology; Proteomes; Serotonin; Serotonin - metabolism; Sex Characteristics; Sex Factors; Sexual dimorphism; Signal transduction; Signal Transduction - physiology; Signaling; Steatosis; Steroid Hydroxylases - genetics; Toxicokinetics and Metabolism; Transcriptome - physiology; Transcriptomes; Drug metabolism; Sexual dimorphism; Lipid metabolism; Hepatocytes; Liver; Cytochrome P450