The role of the systemic inflammatory response in predicting outcomes in patients with operable cancer: Systematic review and meta-analysis

• Published in: Scientific reports Vol. 7; no. 1; pp. 16717 - 31
• Main Authors: Dolan, Ross D., Lim, Jason, McSorley, Stephen T., Horgan, Paul G., McMillan, Donald C.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.12.2017; Nature Publishing Group
• Subjects: 692/4028/546; 692/700/1750/1976; Biomarkers, Tumor - metabolism; Blood Platelets - cytology; Cancer; Humanities and Social Sciences; Humans; Inflammation; Kaplan-Meier Estimate; Literature reviews; Lymphocytes; Lymphocytes - cytology; Meta-analysis; Monocytes; Monocytes - cytology; multidisciplinary; Neoplasms - mortality; Neoplasms - pathology; Neoplasms - surgery; Neutrophils - cytology; Prognosis; Science; Science (multidisciplinary); Systematic review; Tumors

Cancer remains a leading causes of death worldwide and an elevated systemic inflammatory response (SIR) is associated with reduced survival in patients with operable cancer. This review aims to examine the evidence for the role of systemic inflammation based prognostic scores in patients with operab...