Immune cell composition in normal human kidneys

• Published in: Scientific reports Vol. 10; no. 1; p. 15678
• Main Authors: Park, Jun-Gyu, Na, Myeongsu, Kim, Min-Gang, Park, Su Hwan, Lee, Hack June, Kim, Dong Ki, Kwak, Cheol, Kim, Yon Su, Chang, Sunghoe, Moon, Kyung Chul, Lee, Dong-Sup, Han, Seung Seok
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.09.2020; Nature Publishing Group
• Subjects: 631/250/2520; 692/4022; Animals; CCR7 protein; CD11b antigen; CD14 antigen; CD16 antigen; CD3 antigen; CD4 antigen; CD45RA antigen; CD69 antigen; CD8 antigen; Effector cells; Female; Flow cytometry; Genital cancers; Humanities and Social Sciences; Humans; Immunity; Immunohistochemistry; Immunophenotyping; Kidney - immunology; Kidney diseases; Kidneys; Lymphocytes; Lymphocytes T; Macrophages; Male; Malignancy; Memory cells; Mice; multidisciplinary; Myeloid cells; Organ donors; Phenotypes; Science; Science (multidisciplinary); Staining and Labeling
• ISSN: 2045-2322; 2045-2322
• DOI: 10.1038/s41598-020-72821-x

An understanding of immunological mechanisms in kidney diseases has advanced using mouse kidneys. However, the profiling of immune cell subsets in human kidneys remains undetermined, particularly compared with mouse kidneys. Normal human kidneys were obtained from radically nephrectomised patients w...