A combination of platelet-derived and insulin-like growth factors enhances periodontal regeneration

• Published in: Journal of clinical periodontology Vol. 16; no. 8; p. 545
• Main Authors: Lynch, S E, Williams, R C, Polson, A M, Howell, T H, Reddy, M S, Zappa, U E, Antoniades, H N
• Format: Journal Article
• Language: English
• Published: United States 01.09.1989
• Subjects: Alveolar Process - physiology; Animals; Bone Regeneration - drug effects; Connective Tissue - physiology; Dental Cementum - physiology; Dogs; Epithelial Attachment - physiology; Gels; Insulin-Like Growth Factor I - therapeutic use; Periapical Tissue - physiology; Periodontitis - therapy; Periodontium - physiology; Platelet-Derived Growth Factor - therapeutic use; Regeneration - drug effects; Somatomedins - therapeutic use

The combination of platelet-derived growth factor (PDGF) and insulin-like growth factor one (IGF-1) has previously been shown to enhance repair of soft tissue wounds. Here we report initial observations following application of PDGF and IGF-1 to periodontitis-affected teeth in beagle dogs. 1 microgr...