Double‐blind, randomized, placebo‐controlled study of safety, tolerability, pharmacokinetics and pharmacodynamics of TAK‐683, an investigational metastin analogue in healthy men - Scott, Graham; Ahmad, Irfan; Howard, Katy; MacLean, David; Oliva, Cristina; Warrington, Steve; Wilbraham, Darren; Worthington, Paul (British journal of clinical pharmacology, 2013)
Keywords: Aged; Aged, 80 and over; Antineoplastic Agents - adverse effects; Antineoplastic Agents - pharmacokinetics; Antineoplastic Agents - pharmacology; castration‐resistant prostate cancer; Clinical Trials; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Injections, Subcutaneous; Kisspeptins - adverse effects; Kisspeptins - chemistry; Kisspeptins - pharmacokinetics; Kisspeptins - pharmacology; Male; metastin analogue; Middle Aged; pharmacodynamics; pharmacokinetics; TAK‐683; Testosterone - blood