IS4‐FAM, a fluorescent tool to study CXCR4 affinity and competitive antagonism in native cancer cells - Hamshaw, Isabel; Cominetti, Marco M. D.; Nana‐Akyin, Princess; Yee Ho, Ernie Ho; Searcey, Mark; Mueller, Anja (Pharmacology research & perspectives, 2024)
Keywords: antagonist; Antibodies; Binding, Competitive; Cell Line, Tumor; Cells; chemokine receptor; Chemokines; CXCL12; CXCR4; Drug development; Flow Cytometry; Fluorescent Dyes - chemistry; Humans; Leukemia; Ligands; Melanoma; Metastasis; Microscopy; Microscopy, Confocal; Neoplasms - drug therapy; Neoplasms - metabolism; Neoplasms - pathology; PC-3 Cells; Peptides; Pharmacology; Prostate cancer; R&D; Receptors, CXCR4 - antagonists & inhibitors; Receptors, CXCR4 - metabolism; Research & development; Short Report; Skin cancer; Software; United Kingdom--UK; Germany; CXCR4; CXCL12; antagonist; chemokine receptor