On-chip immunofluorescence analysis of single cervical cells using an electroactive microwell array with barrier for cervical screening

• Published in: Biomicrofluidics Vol. 13; no. 4; p. 044107
• Main Authors: Takeuchi, Makoto, Nagasaka, Kazunori, Yoshida, Mina, Kawata, Yoshiko, Miyagawa, Yuko, Tago, Saori, Hiraike, Haruko, Wada-Hiraike, Osamu, Oda, Katsutoshi, Osuga, Yutaka, Fujii, Tomoyuki, Ayabe, Takuya, Kim, Soo Hyeon, Fujii, Teruo
• Format: Journal Article
• Language: English
• Published: United States American Institute of Physics 01.07.2019; AIP Publishing LLC
• Subjects: Arrays; Dielectrophoresis; Efficiency; Human papillomavirus; Immunofluorescence; Medical screening; Microfluidic devices; Regular; Trapping

Several specific tests for cervical screening have been developed recently, including p16/Ki67 dual immunostaining for diagnosing high-risk human papillomavirus positive squamous intraepithelial lesion in the cervix. However, manual screening of cells in an entire glass slide is currently a standard...