Comparison Between Etest and Broth Microdilution Methods for Testing Itraconazole-Resistant Aspergillus fumigatus Susceptibility to Antifungal Combinations

• Published in: Mycopathologia (1975) Vol. 183; no. 2; pp. 359 - 370
• Main Authors: Denardi, Laura Bedin, Keller, Jéssica Tairine, de Azevedo, Maria Isabel, Oliveira, Vanessa, Piasentin, Fernanda Baldissera, Severo, Cecília Bittencourt, Santurio, Janio Morais, Alves, Sydney Hartz
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.04.2018; Springer; Springer Nature B.V
• Subjects: Analysis; Antifungal agents; Aspergillus fumigatus; Assaying; Azoles; Biomedical and Life Sciences; Bone mineral density; Caspofungin; Combination drug therapy; Correlation coefficients; Echinocandins; Eukaryotic Microbiology; Evaluation; Fungi; Fungicides; Heterocyclic compounds; Itraconazole; Life Sciences; Medical Microbiology; Methods; Micafungin; Microbial Ecology; Microbiology; Minimum inhibitory concentration; Plant Sciences; Posaconazole; Reading; Test procedures; Voriconazole; Yard waste; Antifungal combinations; Etest; Broth microdilution; Aspergillus fumigatus

The checkerboard broth microdilution assay (BMD) is the most frequently used method for the in vitro evaluation of drug combinations. However, its use to evaluate the effect of antifungal drugs on filamentous fungi is sometimes associated with endpoint-reading difficulties, and different degrees of...