Retrospective review of severe acute respiratory syndrome coronavirus-2 infection in children with acute leukemia from a tertiary care hospital in Northern India

• Published in: Clinical and experimental pediatrics Vol. 65; no. 3; pp. 150 - 151
• Main Authors: Chhabra, Suhail, Dabas, Aditya, Mittal, Richa, Goel, Neha, Chowdhary, Ritabrata Roy, Batra, Satyendra, Singh, Amitabh, Gera, Rani
• Format: Journal Article
• Language: English
• Published: Korea (South) Clinical and Experimental Pediatics / Korean Pediatric Society 01.03.2022; Korean Pediatric Society; The Korean Pediatric Society; 대한소아청소년과학회
• Subjects: Asymptomatic; Bacterial infections; Cancer therapies; Chemotherapy; Children & youth; Conflicts of interest; Coronaviruses; COVID-19; Disease control; Hematology; Illnesses; Infections; Letter to the Editor; Leukemia; Patients; Pediatrics; Severe acute respiratory syndrome coronavirus 2; Systematic review; 소아과학; India
• ISSN: 2713-4148; 2713-4148
• DOI: 10.3345/cep.2021.01158

The present retrospective study assessed the demographic and clinical characteristics and outcomes of children admitted with acute leukemia at our tertiary care referral center in Northern India with COVID-19 infection. Children who quickly progressed to acute respiratory distress syndrome or respiratory failure and had life-threatening organ dysfunction including shock, encephalopathy, myocardial injury or heart failure, coagulation dysfunction, and acute kidney injury were classified as having a critical illness. Out of 52 children admitted to the COVID-19 pediatric intensive care unit during the study period, 19 were on follow-up for acute leukemia: 12 with B-cell ALL, 5 with T-cell ALL, and 2 with acute myeloid leukemia.