Roles of the HEAT repeat proteins Utp10 and Utp20 in 40S ribosome maturation

• Published in: RNA (Cambridge) Vol. 13; no. 9; pp. 1516 - 1527
• Main Authors: Dez, Christophe, Dlakić, Mensur, Tollervey, David
• Format: Journal Article
• Language: English
• Published: United States Cold Spring Harbor Laboratory Press 01.09.2007
• Subjects: Models, Molecular; Repetitive Sequences, Amino Acid; Ribonucleoproteins, Small Nuclear - genetics; Ribonucleoproteins, Small Nuclear - physiology; Ribonucleoproteins, Small Nucleolar - genetics; Ribonucleoproteins, Small Nucleolar - physiology; RNA Processing, Post-Transcriptional - physiology; RNA, Ribosomal, 18S - biosynthesis; RNA, Small Nucleolar - genetics; RNA, Small Nucleolar - physiology; Saccharomyces cerevisiae; Saccharomyces cerevisiae - genetics; Saccharomyces cerevisiae - growth & development; Saccharomyces cerevisiae - metabolism; Saccharomyces cerevisiae Proteins - genetics; Saccharomyces cerevisiae Proteins - physiology; Signal Transduction - genetics

A family of HEAT-repeat containing ribosome synthesis factors was previously identified in Saccharomyces cerevisiae. We report the detailed characterization of two of these factors, Utp10 and Utp20, which were initially identified as components of the small subunit processome. Coprecipitation analys...