Plasma membrane changes during programmed cell deaths

• Published in: Cell research Vol. 28; no. 1; pp. 9 - 21
• Main Authors: Zhang, Yingying, Chen, Xin, Gueydan, Cyril, Han, Jiahuai
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.01.2018; Nature Publishing Group
• Subjects: 631/250/1933; 631/57/2271; 631/80/82/23; Apoptosis; Biomedical and Life Sciences; Cell Biology; Cell death; Channel pores; Channels; Gangrene; Immune response; Immune system; Immunogenicity; Inflammation; Life Sciences; Lysis; Membranes; Mortality; Necroptosis; Necrosis; Plasma; Plasma membranes; Pore formation; Pores; Pyroptosis; Review; Rupture; Rupturing; morphology; programmed cell death; mechanism; plasma membrane; immunology

Ruptured and intact plasma membranes are classically considered as hallmarks of necrotic and apoptotic cell death, respectively. As such, apoptosis is usually considered a non-inflammatory process while necrosis triggers in- flammation. Recent studies on necroptosis and pyroptosis, two types of prog...