Burden of Infection and Insulin Resistance in Healthy Middle-Aged Men

• Published in: Diabetes care Vol. 29; no. 5; pp. 1058 - 1064
• Main Authors: Fernández-Real, José-Manuel, López-Bermejo, Abel, Vendrell, Joan, Ferri, Maria-José, Recasens, Mónica, Ricart, Wifredo
• Format: Journal Article
• Language: English
• Published: Alexandria, VA American Diabetes Association 01.05.2006
• Subjects: Biological and medical sciences; Cost of Illness; Diabetes. Impaired glucose tolerance; Endocrine pancreas. Apud cells (diseases); Endocrinopathies; Enterovirus Infections - economics; Health Status; Herpes Simplex - economics; Herpesvirus 1, Human - isolation & purification; Herpesvirus 2, Human - isolation & purification; Humans; Insulin - blood; Insulin - metabolism; Insulin Resistance; Insulin Secretion; Male; Medical sciences; Middle Aged; Spain; Spain; Endocrinopathy; Human; Pancreatic hormone; Chlamydia pneumoniae; Middle age; Chlamydiaceae; Picornaviridae; Herpesviridae; Alphaherpesvirinae; Male; Enterovirus; Inflammation; Insulin; Virus; Infection; Target tissue resistance; Chlamydiales; Human herpesvirus 2; Bacteria; Adult; Human herpesvirus 1; Insulin resistance; Herpesvirus hominis

OBJECTIVE:--We hypothesized that burden of infection could be associated with chronic low-grade inflammation, resulting in insulin resistance. We aimed to study the effect of exposure to four infections on insulin sensitivity in apparently healthy middle-aged men (n = 124). RESEARCH DESIGN AND METHO...