Pretransplantation Inflammatory and Nutritional Status in Elderly Allogeneic Hematopoietic Stem Cell Transplantation: Prognostic Value of C-Reactive Protein-to-Albumin Ratio

• Published in: Transplantation and cellular therapy Vol. 30; no. 4; pp. 400.e1 - 400.e9
• Main Authors: Miyazaki, Takuya, Tachibana, Takayoshi, Suzuki, Taisei, Izumi, Akihiko, Fujimaki, Katsumichi, Sato, Shuku, Tamai, Yotaro, Michishita, Yusuke, Suzuki, Takahiro, Ishii, Ryuji, Hirasawa, Akira, Hashimoto, Chizuko, Kabasawa, Nobuyuki, Inoue, Yasuyuki, Ishiyama, Taijiro, Yamamoto, Koh, Kanamori, Heiwa, Tanaka, Masatsugu, Nakajima, Hideaki
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2024
• Subjects: Aged; Allogeneic hematopoietic stem cell transplantation; Biomarkers; C-Reactive Protein - analysis; C-Reactive Protein - chemistry; C-reactive protein-to-albumin ratio; Elderly transplantation; Hematologic Neoplasms - therapy; Hematopoietic Stem Cell Transplantation - adverse effects; Humans; Inflammation - diagnosis; Inflammation and nutrition; Nutritional Status; Prognosis; Prognostic factor; Retrospective Studies; Serum Albumin - analysis; Serum Albumin - chemistry; Transplantation, Homologous - adverse effects; Elderly transplantation; Prognostic factor; Allogeneic hematopoietic stem cell transplantation; C-reactive protein-to-albumin ratio; Inflammation and nutrition

•Biomarkers were compared in elderly patients undergoing allogeneic HSCT.•C-reactive protein-to-albumin ratio (CAR) was the most useful prognostic indicator for HSCT in elderly patients.•CAR is a powerful patient-related risk factor independent of HCT-CI score. There are no clear criteria for select...