Hippocampal and parahippocampal volumes in schizophrenia : A structural MRI study

• Published in: Schizophrenia bulletin Vol. 32; no. 2; pp. 332 - 340
• Main Authors: SIM, Kang, DEWITT, Iain, DITMAN, Tali, ZALESAK, Martin, GREENHOUSE, Ian, GOFF, Donald, WEISS, Anthony P, HECKERS, Stephan
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.04.2006; Oxford Publishing Limited (England)
• Subjects: Adult; Adult and adolescent clinical studies; Biological and medical sciences; Cerebral Cortex - anatomy & histology; Diagnostic and Statistical Manual of Mental Disorders; Female; Hippocampus - anatomy & histology; Hippocampus - physiopathology; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Parahippocampal Gyrus - anatomy & histology; Parahippocampal Gyrus - physiopathology; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Regular; Schizophrenia; Schizophrenia - physiopathology; Temporal Lobe - anatomy & histology; Psychosis; Temporal lobe; Volumetric analysis; Central nervous system; ParahIppocampal cortex; Schizophrenia; Medical imagery; medial temporal lobe/entorhinal/perirhinal/ parahippocampal/region/functional; Nuclear magnetic resonance imaging; Hippocampus; Encephalon

Smaller medial temporal lobe volume is a frequent finding in studies of patients with schizophrenia, but the relative contributions of the hippocampus and three surrounding cortical regions (entorhinal cortex, perirhinal cortex, and parahippocampal cortex) are poorly understood. We tested the hypoth...