Validity of magnetic resonance imaging (MRI) in the primary spinal cord tumors in routine clinical setting
Abstract MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical practice, where MRI tissue diagnosis is usually not a single one but multiple ones with several differential diagnoses. Here, we aimed to asse...
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Published in | Scientific reports Vol. 12; no. 1; p. 10151 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
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16.06.2022
Nature Publishing Group UK Nature Portfolio |
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Abstract | Abstract
MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical practice, where MRI tissue diagnosis is usually not a single one but multiple ones with several differential diagnoses. Here, we aimed to assess the validity of MRI in terms of predicting the pathology and location of the tumor in routine clinical settings. We analyzed 820 patients with primary spinal cord tumors, who have a pathological diagnosis and location in the operation record which were confirmed. We modified traditional measures for validity based upon a set of diagnoses instead of a single diagnosis. Sensitivity and specificity and positive and negative predictabilities were evaluated for the tumor location and pathology. For tumor location, 456 were intradural extramedullary; 165 were intramedullary, and 156 were extradural. The overall sensitivity and specificity were over 90.0%. However, the sensitivity became lower when the tumor resided simultaneously in two spaces such as in the intradural-and-extradural or intramedullary-and-extramedullary space (54.6% and 30.0%, respectively). Most common pathology was schwannoma (n = 416), followed by meningioma (114) and ependymoma (87). Sensitivities were 93.3%, 90.4%, and 89.7%, respectively. Specificities were 70.8%, 82.9%, and 76.0%. In rare tumors such as neurofibromas, and diffuse midline gliomas, the sensitivity was much lower (less than 30%). For common locations and pathologies, the validity of MRI is generally acceptable. However, for rare locations and pathologies, MRI diagnosis still needs some improvement. |
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AbstractList | Abstract
MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical practice, where MRI tissue diagnosis is usually not a single one but multiple ones with several differential diagnoses. Here, we aimed to assess the validity of MRI in terms of predicting the pathology and location of the tumor in routine clinical settings. We analyzed 820 patients with primary spinal cord tumors, who have a pathological diagnosis and location in the operation record which were confirmed. We modified traditional measures for validity based upon a set of diagnoses instead of a single diagnosis. Sensitivity and specificity and positive and negative predictabilities were evaluated for the tumor location and pathology. For tumor location, 456 were intradural extramedullary; 165 were intramedullary, and 156 were extradural. The overall sensitivity and specificity were over 90.0%. However, the sensitivity became lower when the tumor resided simultaneously in two spaces such as in the intradural-and-extradural or intramedullary-and-extramedullary space (54.6% and 30.0%, respectively). Most common pathology was schwannoma (n = 416), followed by meningioma (114) and ependymoma (87). Sensitivities were 93.3%, 90.4%, and 89.7%, respectively. Specificities were 70.8%, 82.9%, and 76.0%. In rare tumors such as neurofibromas, and diffuse midline gliomas, the sensitivity was much lower (less than 30%). For common locations and pathologies, the validity of MRI is generally acceptable. However, for rare locations and pathologies, MRI diagnosis still needs some improvement. MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical practice, where MRI tissue diagnosis is usually not a single one but multiple ones with several differential diagnoses. Here, we aimed to assess the validity of MRI in terms of predicting the pathology and location of the tumor in routine clinical settings. We analyzed 820 patients with primary spinal cord tumors, who have a pathological diagnosis and location in the operation record which were confirmed. We modified traditional measures for validity based upon a set of diagnoses instead of a single diagnosis. Sensitivity and specificity and positive and negative predictabilities were evaluated for the tumor location and pathology. For tumor location, 456 were intradural extramedullary; 165 were intramedullary, and 156 were extradural. The overall sensitivity and specificity were over 90.0%. However, the sensitivity became lower when the tumor resided simultaneously in two spaces such as in the intradural-and-extradural or intramedullary-and-extramedullary space (54.6% and 30.0%, respectively). Most common pathology was schwannoma (n = 416), followed by meningioma (114) and ependymoma (87). Sensitivities were 93.3%, 90.4%, and 89.7%, respectively. Specificities were 70.8%, 82.9%, and 76.0%. In rare tumors such as neurofibromas, and diffuse midline gliomas, the sensitivity was much lower (less than 30%). For common locations and pathologies, the validity of MRI is generally acceptable. However, for rare locations and pathologies, MRI diagnosis still needs some improvement. Abstract MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical practice, where MRI tissue diagnosis is usually not a single one but multiple ones with several differential diagnoses. Here, we aimed to assess the validity of MRI in terms of predicting the pathology and location of the tumor in routine clinical settings. We analyzed 820 patients with primary spinal cord tumors, who have a pathological diagnosis and location in the operation record which were confirmed. We modified traditional measures for validity based upon a set of diagnoses instead of a single diagnosis. Sensitivity and specificity and positive and negative predictabilities were evaluated for the tumor location and pathology. For tumor location, 456 were intradural extramedullary; 165 were intramedullary, and 156 were extradural. The overall sensitivity and specificity were over 90.0%. However, the sensitivity became lower when the tumor resided simultaneously in two spaces such as in the intradural-and-extradural or intramedullary-and-extramedullary space (54.6% and 30.0%, respectively). Most common pathology was schwannoma (n = 416), followed by meningioma (114) and ependymoma (87). Sensitivities were 93.3%, 90.4%, and 89.7%, respectively. Specificities were 70.8%, 82.9%, and 76.0%. In rare tumors such as neurofibromas, and diffuse midline gliomas, the sensitivity was much lower (less than 30%). For common locations and pathologies, the validity of MRI is generally acceptable. However, for rare locations and pathologies, MRI diagnosis still needs some improvement. |
ArticleNumber | 10151 |
Author | Yuh, Woon Tak Kwon, Shin Won Won, Young Il Choi, Yunhee Chung, Chun Kee Kim, Chi Heon Yang, Seung Heon |
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CitedBy_id | crossref_primary_10_1007_s00500_023_08826_1 crossref_primary_10_1016_j_jddst_2022_103758 crossref_primary_10_25259_SNI_636_2023 crossref_primary_10_1016_j_wneu_2024_05_106 crossref_primary_10_1016_j_patol_2024_03_002 |
Cites_doi | 10.1016/j.jos.2017.11.012 10.1007/s00701-013-1760-7 10.1007/s00234-016-1744-4 10.3171/jns.1987.67.4.0518 10.1007/978-981-15-7771-0_10 10.1007/s11060-016-2239-1 10.1111/j.1552-6569.2003.tb00202.x 10.3171/2015.5.FOCUS15158 10.1023/a:1021297622944 10.1038/sc.2008.89 10.2214/ajr.178.1.1780201 10.1007/s10143-018-0957-x 10.1148/radiographics.20.6.g00nv151721 10.1007/s11547-019-00988-z 10.3340/jkns.2016.0505.011 10.2214/ajr.174.2.1740377 10.1007/s11910-011-0190-2 10.1038/sj.sc.3101668 10.3340/jkns.2007.42.6.436 10.1007/s00234-007-0345-7 10.1038/sc.2014.127 10.1016/j.ejrad.2003.10.021 10.1148/rg.2019180200 10.1016/j.ijsu.2016.10.023 |
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References_xml | – volume: 23 start-page: 408 year: 2018 ident: 13881_CR6 publication-title: J. Orthop. Sci. doi: 10.1016/j.jos.2017.11.012 contributor: fullname: E Iwata – volume: 155 start-page: 1209 year: 2013 ident: 13881_CR15 publication-title: Acta Neurochir. (Wien) doi: 10.1007/s00701-013-1760-7 contributor: fullname: KM Kim – volume: 58 start-page: 1117 year: 2016 ident: 13881_CR8 publication-title: Neuroradiology doi: 10.1007/s00234-016-1744-4 contributor: fullname: T Gong – volume: 67 start-page: 518 year: 1987 ident: 13881_CR20 publication-title: J. Neurosurg. doi: 10.3171/jns.1987.67.4.0518 contributor: fullname: D Rigamonti – ident: 13881_CR17 doi: 10.1007/978-981-15-7771-0_10 – volume: 130 start-page: 229 year: 2016 ident: 13881_CR21 publication-title: J. Neurooncol. doi: 10.1007/s11060-016-2239-1 contributor: fullname: I Jeon – volume: 13 start-page: 346 year: 2003 ident: 13881_CR25 publication-title: J. Neuroimaging doi: 10.1111/j.1552-6569.2003.tb00202.x contributor: fullname: B Sun – volume: 39 start-page: E14 year: 2015 ident: 13881_CR26 publication-title: Neurosurg. Focus doi: 10.3171/2015.5.FOCUS15158 contributor: fullname: MK Tobin – volume: 61 start-page: 27 year: 2003 ident: 13881_CR13 publication-title: J. Neurooncol. doi: 10.1023/a:1021297622944 contributor: fullname: DK Lee – volume: 47 start-page: 128 year: 2009 ident: 13881_CR16 publication-title: Spinal Cord doi: 10.1038/sc.2008.89 contributor: fullname: SB Park – ident: 13881_CR22 doi: 10.2214/ajr.178.1.1780201 – volume: 20 start-page: 1373 year: 1999 ident: 13881_CR23 publication-title: AJNR Am. J. Neuroradiol. contributor: fullname: K Kono – volume: 42 start-page: 371 year: 2019 ident: 13881_CR9 publication-title: Neurosurg. Rev. doi: 10.1007/s10143-018-0957-x contributor: fullname: M Ottenhausen – volume: 20 start-page: 1721 year: 2000 ident: 13881_CR4 publication-title: Radiographics doi: 10.1148/radiographics.20.6.g00nv151721 contributor: fullname: KK Koeller – volume: 124 start-page: 510 year: 2019 ident: 13881_CR7 publication-title: Radiol. Med. doi: 10.1007/s11547-019-00988-z contributor: fullname: XD Zhai – volume: 60 start-page: 195 year: 2017 ident: 13881_CR14 publication-title: J. Korean Neurosurg. Soc. doi: 10.3340/jkns.2016.0505.011 contributor: fullname: S Sohn – volume: 174 start-page: 377 year: 2000 ident: 13881_CR19 publication-title: AJR Am. J. Roentgenol. doi: 10.2214/ajr.174.2.1740377 contributor: fullname: KB Baker – volume: 11 start-page: 320 year: 2011 ident: 13881_CR1 publication-title: Curr. Neurol. Neurosci. Rep. doi: 10.1007/s11910-011-0190-2 contributor: fullname: MC Chamberlain – volume: 43 start-page: 34 year: 2005 ident: 13881_CR5 publication-title: Spinal Cord doi: 10.1038/sj.sc.3101668 contributor: fullname: IE Sandalcioglu – volume: 42 start-page: 436 year: 2007 ident: 13881_CR12 publication-title: J. Korean Neurosurg. Soc. doi: 10.3340/jkns.2007.42.6.436 contributor: fullname: JH Na – volume: 50 start-page: 301 year: 2008 ident: 13881_CR24 publication-title: Neuroradiology doi: 10.1007/s00234-007-0345-7 contributor: fullname: K Abul-Kasim – volume: 22 start-page: 206 year: 2001 ident: 13881_CR11 publication-title: AJNR Am. J. Neuroradiol. contributor: fullname: BC Chu – volume: 52 start-page: 769 year: 2014 ident: 13881_CR3 publication-title: Spinal Cord doi: 10.1038/sc.2014.127 contributor: fullname: H Arima – volume: 50 start-page: 159 year: 2004 ident: 13881_CR10 publication-title: Eur. J. Radiol. doi: 10.1016/j.ejrad.2003.10.021 contributor: fullname: JW Van Goethem – volume: 39 start-page: 468 year: 2019 ident: 13881_CR2 publication-title: Radiographics doi: 10.1148/rg.2019180200 contributor: fullname: KK Koeller – volume: 36 start-page: 109 year: 2016 ident: 13881_CR18 publication-title: Int. J. Surg. doi: 10.1016/j.ijsu.2016.10.023 contributor: fullname: PF Yan |
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Snippet | Abstract
MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical... MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical practice,... Abstract MRI is the primary diagnostic modality for spinal cord tumors. However, its validity has never been vigorously scrutinized in daily routine clinical... |
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SubjectTerms | Diagnosis Magnetic resonance imaging Meningioma Pathology Schwann cells Spinal cancer Spinal cord Tumors Validity |
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Title | Validity of magnetic resonance imaging (MRI) in the primary spinal cord tumors in routine clinical setting |
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